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Evaluation of suitable porosity for sintered porous {beta}-tricalcium phosphate as a bone substitute

Journal Article · · Materials Characterization
;  [1];  [2];  [1]
  1. School of Mechanical Systems Engineering, Chonnam National University, 300 Yongbong-dong, Buk-gu, Gwangju, 500-757 (Korea, Republic of)
  2. INJECTA Inc., 1511 Gwanyang-dong, Dongan-gu, Anyang-si, 431-809 (Korea, Republic of)

Structural and mechanical characterization is performed for sintered porous beta tricalcium phosphate ({beta}-TCP) to determine the appropriate porosity for use as a bone substitute. Four different types of porous {beta}-TCP specimen with different porosities are fabricated through a sintering process. For structural characterization, scanning electron microscopy and a Microfocus X-ray computed tomography system are used to investigate the pore openings on the specimen's surface, pore size, pore distribution, and pore interconnections. Compression tests of the specimens are performed, and mechanical properties such as the elastic modulus and compressive strength are obtained. Also, the geometric shape and volume of the {beta}-TCP around the contact region of two pores, which need to be initially resolved after implantation in order to increase the size of the pore openings, are evaluated through simple calculations. The results show that porous {beta}-TCP with 42.1% porosity may be a suitable bone substitute candidate in terms of sustaining external loads, and inducing and cultivating bone cells. - Highlights: Black-Right-Pointing-Pointer Structural and mechanical characterization was performed for sintered porous {beta}-TCP specimens. Black-Right-Pointing-Pointer For structural characterization, SEM and Microfocus X-ray CT system were used. Black-Right-Pointing-Pointer For mechanical characterization, compression tests were performed. Black-Right-Pointing-Pointer Porous {beta}-TCP with 42.1% porosity may be a suitable bone substitute.

OSTI ID:
22163129
Journal Information:
Materials Characterization, Journal Name: Materials Characterization Journal Issue: Complete Vol. 71; ISSN 1044-5803; ISSN MACHEX
Country of Publication:
United States
Language:
English

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