Measurement of cross sections for the {sup 232}Th(P,4n){sup 229}Pa reaction at low proton energies
- Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States)
- Department of Nuclear Engineering, University of Tennessee, Knoxville, TN 37996, USA and Fuel Cycle and Isotopes Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States)
- Fuel Cycle and Isotopes Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States)
- Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States)
- Oak Ridge Associated Universities, Oak Ridge, TN 37831 (United States)
The alpha-emitters {sup 225}Ac and {sup 213}Bi are of great interest for alpha-radioimmunotherapy which uses radioisotopes attached to cancer-seeking antibodies to efficiently treat various types of cancers. Both radioisotopes are daughters of the long-lived {sup 229}Th(t{sub 1/2} = 7880y). {sup 229}Th can be produced by proton irradiation of {sup 232}Th and {sup 230}Th, either directly or through production of isobars that beta-decay into {sup 229}Th. To obtain excitation functions, {sup 232}Th and {sup 230}Th have been irradiated at the On-Line Test Facility at the Holifield Radioactive Ion Beam Facility at ORNL. Benchmark tests conducted with Cu and Ni foils show very good agreement with literature results. The experiments with thorium targets were focused on the production of {sup 229}Pa and its daughter {sup 225}Ac from both {sup 232}Th and {sup 230}Th. Differential cross-sections for production of {sup 229}Pa and other Pa isotopes have been obtained.
- OSTI ID:
- 22117004
- Journal Information:
- AIP Conference Proceedings, Journal Name: AIP Conference Proceedings Journal Issue: 1 Vol. 1525; ISSN APCPCS; ISSN 0094-243X
- Country of Publication:
- United States
- Language:
- English
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