Synthesis of labeled compounds using recovered tritium from expired beta light sources

Journal Article · Tue Jul 15 04:00:00 UTC 2008 · Fusion Science and Technology

OSTI ID:22109425

Matei, L.; Postolache, C.; Bubueanu, G. ^[1]; Podina, C. ^[2]

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1. National Inst. of Research and Development for Physics and Nuclear Engineering Horia Hulubei, street Atomistilor 407, Magurele, Bucharest (Romania)
2. Univ. of Bucharest, Faculty of Chemistry, 4-12 Regina Elisabeta blv., Bucharest (Romania)

In this paper, the technological procedures for extracting tritium from beta light source are highlighted. The recovered tritium was used in the synthesis of organically labeled compounds and in the preparation of tritiated water (HTO) with high specific activity. Technological procedures for treatment of beta light sources consist of: envelope breaking into evacuated enclosure, the radioactive gaseous mixture pumping and its storage on metallic sodium. The mixtures of T{sub 2} and {sup 3}He were used in the synthesis of tritium labeled steroid hormones, nucleosides analogues and for the preparation of HTO with high radioactivity concentrations. (authors)

• OSTI ID: 22109425
• Journal Information: Fusion Science and Technology, Journal Name: Fusion Science and Technology Journal Issue: 2 Vol. 54; ISSN 1536-1055
• Country of Publication: United States
• Language: English

Related Subjects

07 ISOTOPE AND RADIATION SOURCES
ARSENIC COMPOUNDS
CHLORINE COMPOUNDS
HELIUM 3
LABELLED COMPOUNDS
LIGHT SOURCES
MIXTURES
NUCLEOSIDES
RADIOACTIVITY
SODIUM
STEROID HORMONES
STORAGE
SYNTHESIS
TRITIUM