Routine {sup 18}F{sup -} production with 180 {mu}A to 200 {mu}A target beam current on a GE PETtrace 800 cyclotron

Journal Article · Wed Dec 19 00:00:00 EST 2012 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.4773942· OSTI ID:22075954

Eberl, S; Eriksson, T; Svedberg, O; Norling, J; Henderson, D; Lam, P; Bourdier, T; Fulham, M ^[1]

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1. Department of PET and Nuclear Medicine, Royal Prince Alfred Hospital, Sydney, NSW (Australia)

Through upgrades and enhancements, which are now standard on current PETtrace 800 cyclotrons, a GE PETtrace cyclotron installed in 2002 has demonstrated reliable routine [{sup 18}F]FDG production at total target beam currents of 180 {mu}A without detriment to saturation and [{sup 18}F]FDG yields. Routine production at 200 {mu}A has been achieved and its evaluation is continuing. Self-shielded target using W/Cu alloy for the target body afforded a reduction in dose rate from the Havar foils by a factor of {approx} 8-10, reducing dose from the targets and need for removing targets during maintenance. The main activation product in the shield is {sup 187}W (T1/2 24 h). The {sup 60}Co ((T1/2 5.3 y) activation is about 250 times less at 24 h post EOB and is not considered a major issue despite its long half-life.

• OSTI ID: 22075954
• Journal Information: AIP Conference Proceedings, Vol. 1509, Issue 1; Conference: 14. international workshop on targetry and target chemistry, Playa del Carmen (Mexico), 26-29 Aug 2012; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY
RADIOCHEMISTRY AND NUCLEAR CHEMISTRY
43 PARTICLE ACCELERATORS
BEAM CURRENTS
CHEMICAL REACTION YIELD
COBALT 60
CYCLOTRONS
DOSE RATES
DOSIMETRY
FLUORINE
FLUORINE 18
FOILS
HALF-LIFE
HAVAR
ISOTOPE PRODUCTION
NUCLEAR REACTION YIELD
PARTICLE BEAMS
PROTON REACTIONS
REDUCTION
TUNGSTEN 187