A gain and bandwidth enhanced transimpedance preamplifier for Fourier-transform ion cyclotron resonance mass spectrometry

Journal Article · Thu Dec 15 00:00:00 EST 2011 · Review of Scientific Instruments

DOI:https://doi.org/10.1063/1.3660778· OSTI ID:22062390

Lin, Tzu-Yung; Green, Roger J ^[1]; O'Connor, Peter B ^[2]

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1. School of Engineering, University of Warwick, Coventry (United Kingdom)
2. Department of Chemistry, University of Warwick, Coventry (United Kingdom)

The nature of the ion signal from a 12-T Fourier-transform ion cyclotron resonance mass spectrometer and the electronic noise were studied to further understand the electronic detection limit. At minimal cost, a new transimpedance preamplifier was designed, computer simulated, built, and tested. The preamplifier design pushes the electronic signal-to-noise performance at room temperature to the limit, because of its enhanced tolerance of the capacitance of the detection device, lower intrinsic noise, and larger flat mid-band gain (input current noise spectral density of around 1 pA/{radical}(Hz) when the transimpedance is about 85 dB{Omega}). The designed preamplifier has a bandwidth of {approx}3 kHz to 10 MHz, which corresponds to the mass-to-charge ratio, m/z, of approximately 18 to 61 k at 12 T. The transimpedance and the bandwidth can be easily adjusted by changing the value of passive components. The feedback limitation of the circuit is discussed. With the maximum possible transimpedance of 5.3 M{Omega} when using an 0402 surface mount resistor, the preamplifier was estimated to be able to detect {approx}110 charges in a single scan.

• OSTI ID: 22062390
• Journal Information: Review of Scientific Instruments, Vol. 82, Issue 12; Other Information: (c) 2011 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0034-6748
• Country of Publication: United States
• Language: English

Related Subjects

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
CAPACITANCE
COMPUTERIZED SIMULATION
COST
DESIGN
FOURIER TRANSFORM SPECTROMETERS
GAIN
ION CYCLOTRON-RESONANCE
KHZ RANGE
MASS SPECTROSCOPY
MHZ RANGE
MINUS-PLUS RATIO
PREAMPLIFIERS
RESISTORS
SENSITIVITY
SIGNAL-TO-NOISE RATIO
SPECTRAL DENSITY
TEMPERATURE RANGE 0273-0400 K
TOLERANCE