Application of synchrotron radiation computed microtomography for quantification of bone microstructure in human and rat bones

Journal Article · Thu May 17 00:00:00 EDT 2012 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.3703340· OSTI ID:22004044

Parreiras Nogueira, Liebert; Barroso, Regina Cely; Pereira de Almeida, Andre; Braz, Delson; Almeida, Carlos Eduardo de; Borba de Andrade, Cherley; Tromba, Giuliana ^[1]

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1. Nuclear Instrumentation Laboratory / COPPE / UFRJ, P.O. Box 68509, 21945-970, Rio de Janeiro (Brazil)

This work aims to evaluate histomorphometric quantification by synchrotron radiation computed microto-mography in bones of human and rat specimens. Bones specimens are classified as normal and pathological (for human samples) and irradiated and non-irradiated samples (for rat ones). Human bones are specimens which were affected by some injury, or not. Rat bones are specimens which were irradiated, simulating radiotherapy procedures, or not. Images were obtained on SYRMEP beamline at the Elettra Synchrotron Laboratory in Trieste, Italy. The system generated 14 {mu}m tomographic images. The quantification of bone structures were performed directly by the 3D rendered images using a home-made software. Resolution yielded was excellent what facilitate quantification of bone microstructures.

• OSTI ID: 22004044
• Journal Information: AIP Conference Proceedings, Vol. 1437, Issue 1; Conference: 21. international congress on X-ray optics and microanalysis, Campinas (Brazil), 5-9 Sep 2011; Other Information: (c) 2012 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
60 APPLIED LIFE SCIENCES
COMPUTER CODES
COMPUTER GRAPHICS
COMPUTERIZED TOMOGRAPHY
HUMAN POPULATIONS
IMAGE PROCESSING
IMAGES
INJURIES
MICROSTRUCTURE
RADIOTHERAPY
RATS
RESOLUTION
SKELETON
SYNCHROTRON RADIATION