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Title: Estimation of reactogenicity of preparations produced on the basis of photoinactivated live vaccines against brucellosis and tularaemia on the organismic level. 1. Using the LASCA method

Journal Article · · Quantum Electronics (Woodbury, N.Y.)

A new method of photoinactivation of bacteria aimed at producing prototypes of vaccine preparations against extremely dangerous infections is described. The reactogenicity of the new prophylactic preparations was studied using the laser speckle contrast analysis (LASCA). The performed experimental studies show that bacterial suspensions, irradiated using different regimes of photoinactivation, do not cause detrimental effect on the blood microcirculation in laboratory animals. (optical technologies in biophysics and medicine)

OSTI ID:
21550404
Journal Information:
Quantum Electronics (Woodbury, N.Y.), Vol. 41, Issue 4; Other Information: DOI: 10.1070/QE2011v041n04ABEH014598; ISSN 1063-7818
Country of Publication:
United States
Language:
English