Effect of soil on the bioavailability of chemical components of manufactured gas plant residue
- Rutgers, State Univ. of New Jersey, Piscataway, NJ (United States)
This investigation was undertaken to evaluate the bioavailability of polycyclic aromatic hydrocarbons from manufactured gas plant residue (MGP) in soils. Pyrene metabolite excretion in urine and chemical:DNA adduct formation in forestomach and lung of mice were used as indicators of bioavailability. Analyses of excretion data indicated that the bioavailability of pyrene from neat MGP and soils contaminated with MGP was 35 to 52% and 1 to 6%, respectively. Generally, the bioavailability of pyrene was considerably decreased when MGP is adsorbed on soil particles. Chemical:DNA data indicated that the bioavailability of the PAH responsible for chemical:DNA adduct formation varies between soil samples. In addition, these data suggest that urinary PAH metabolites may not provide an accurate assessment of the bioavailability of the compounds responsible for DNA adduct formation.
- OSTI ID:
- 210363
- Report Number(s):
- CONF-9509139-; TRN: 95:008324-0204
- Resource Relation:
- Conference: 7. ACS special symposium: emerging technologies in hazardous waste management, Atlanta, GA (United States), 17-20 Sep 1995; Other Information: PBD: 1995; Related Information: Is Part Of Emerging technologies in hazardous waste management VII; Tedder, D.W. [ed.]; PB: 1352 p.
- Country of Publication:
- United States
- Language:
- English
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