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Ion focusing device

Patent ·
OSTI ID:1987226

Apparatus include a plurality of electrode arrangements spaced apart from each other opposite an ion propagation axis and defining an ion transfer channel that extends along the ion propagation axis that tapers between an input end that is situated to receive ions and an output end that is situated to couple the received ions to an input end of an ion guide. Methods include positioning a plurality of electrode arrangements at oblique angles opposite an ion propagation axis so as to form a ion transfer channel that tapers between an input end and an output end, and coupling the output end of the ion transfer channel to an input end of an ion optical element so as to direct ions in the ion transfer channel into the ion optical element. Related systems are also disclosed.

Research Organization:
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Number(s):
11,605,531
Application Number:
16/956,858
OSTI ID:
1987226
Country of Publication:
United States
Language:
English

References (18)

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Ion Trapping for Ion Mobility Spectrometry Measurements in a Cyclical Drift Tube journal July 2013
Simulation of Electric Potentials and Ion Motion in Planar Electrode Structures for Lossless Ion Manipulations (SLIM) journal September 2014
Development of a new ion mobility time-of-flight mass spectrometer journal February 2015
Applications of a travelling wave-based radio-frequency-only stacked ring ion guide
  • Giles, Kevin; Pringle, Steven D.; Worthington, Kenneth R.
  • Rapid Communications in Mass Spectrometry, Vol. 18, Issue 20, p. 2401-2414 https://doi.org/10.1002/rcm.1641
journal October 2004
Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations journal September 2014
Experimental Evaluation and Optimization of Structures for Lossless Ion Manipulations for Ion Mobility Spectrometry with Time-of-Flight Mass Spectrometry journal September 2014
Fundamentals of Traveling Wave Ion Mobility Spectrometry journal December 2008
Deciphering Drift Time Measurements from Travelling Wave Ion Mobility Spectrometry-Mass Spectrometry Studies journal April 2009
Enhancements in travelling wave ion mobility resolution
  • Giles, Kevin; Williams, Jonathan P.; Campuzano, Iain
  • Rapid Communications in Mass Spectrometry, Vol. 25, Issue 11, p. 1559-1566 https://doi.org/10.1002/rcm.5013
journal May 2011
A method for direct measurement of ion mobilities using a travelling wave ion guide journal December 2010
A Tandem Mass Spectrometer for Improved Transmission and Analysis of Large Macromolecular Assemblies journal March 2002
Effects of Select Anions from the Hofmeister Series on the Gas-Phase Conformations of Protein Ions Measured with Traveling-Wave Ion Mobility Spectrometry/Mass Spectrometry journal September 2011
Ion Trapping, Storage, and Ejection in Structures for Lossless Ion Manipulations journal May 2015
New frontiers for mass spectrometry based upon structures for lossless ion manipulations journal January 2017
Characterization of Ion Dynamics in Structures for Lossless Ion Manipulations journal September 2014
Characterization of Traveling Wave Ion Mobility Separations in Structures for Lossless Ion Manipulations journal October 2015

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