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U.S. Department of Energy
Office of Scientific and Technical Information

Biosynthetic platform for the production of cannabinoids and other prenylated compounds

Patent ·
OSTI ID:1986733
Provided is an enzyme useful for prenylation and recombinant pathways for the production of cannabinoids, cannabinoid precursors and other prenylated chemicals in a cell free system as well and recombinant microorganisms that catalyze the reactions.
Research Organization:
University of California, Los Angeles, CA (United States)
Sponsoring Organization:
USDOE; National Institutes of Health (NIH)
DOE Contract Number:
FC02-02ER63421
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
11,479,760
Application Number:
17/264,758
OSTI ID:
1986733
Country of Publication:
United States
Language:
English

References (5)

Engineering yeasts as platform organisms for cannabinoid biosynthesis journal October 2017
A bio-inspired cell-free system for cannabinoid production from inexpensive inputs journal August 2020
Structure-Based Engineering Increased the Catalytic Turnover Rate of a Novel Phenazine Prenyltransferase journal October 2012
Catalytic Mechanism of Aromatic Prenylation by NphB journal March 2012
A cell-free platform for the prenylation of natural products and application to cannabinoid production journal February 2019

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