In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption

Yang, Yang; Ako-Adounvo, Ann-Marie; Wang, Jiang; Coelho, Sergio G.; Adah, Steven A.; Matta, Murali K.; Strauss, David; Michele, Theresa M.; Wang, Jian; Faustino, Patrick J.; O’Connor, Thomas; Ashraf, Muhammad

doi:10.1208/s12249-022-02275-z

In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption

Journal Article · 22 April 2022 · AAPS PharmSciTech

DOI:https://doi.org/10.1208/s12249-022-02275-z· OSTI ID:1983044

; Ako-Adounvo, Ann-Marie; Wang, Jiang; Coelho, Sergio G.; Adah, Steven A.; Matta, Murali K.; Strauss, David; Michele, Theresa M.; Wang, Jian; Faustino, Patrick J.; O’Connor, Thomas; Ashraf, Muhammad

Not provided.

Research Organization:: Oak Ridge Inst. for Science and Education (ORISE), Oak Ridge, TN (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

DOE Contract Number:: SC0014664

OSTI ID:: 1983044

Journal Information:: AAPS PharmSciTech, Vol. 23, Issue 5; ISSN 1530-9932

Publisher:: Springer

Country of Publication:: United States

Language:: English

References (16)

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Systemic Absorption of the Sunscreens Benzophenone-3, Octyl-Methoxycinnamate, and 3-(4-Methyl-Benzylidene) Camphor After Whole-Body Topical Application and Reproductive Hormone Levels in Humans Janjua, Nadeem Rezaq; Mogensen, Brian; Andersson, Anna-Maria Journal of Investigative Dermatology, Vol. 123, Issue 1 https://doi.org/10.1111/j.0022-202X.2004.22725.x	journal	July 2004
Sunscreens in human plasma and urine after repeated whole-body topical application Janjua, Nr; Kongshoj, B.; Andersson, A-M Journal of the European Academy of Dermatology and Venereology, Vol. 22, Issue 4 https://doi.org/10.1111/j.1468-3083.2007.02492.x	journal	April 2008
Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity Watanabe, Yoko; Kojima, Hiroyuki; Takeuchi, Shinji Toxicology and Applied Pharmacology, Vol. 282, Issue 2 https://doi.org/10.1016/j.taap.2014.12.002	journal	January 2015
In Vitro Testing of Sunscreens for Dermal Absorption: A Platform for Product Selection for Maximal Usage Clinical Trials Yang, Yang; Ako-Adounvo, Ann-Marie; Wang, Jiang Journal of Investigative Dermatology, Vol. 140, Issue 12 https://doi.org/10.1016/j.jid.2020.04.009	journal	December 2020
Skin models for the testing of transdermal drugs Abd, Eman; Yousuf, Shereen; Pastore, Michael Clinical Pharmacology: Advances and Applications, Vol. Volume 8 https://doi.org/10.2147/CPAA.S64788	journal	October 2016
Influence of Physicochemical Properties on the In Vitro Skin Permeation of the Enantiomers, Racemate, and Eutectics of Ibuprofen for Enhanced Transdermal Drug Delivery Yuan, Xudong; Capomacchia, Anthony C. Journal of Pharmaceutical Sciences, Vol. 102, Issue 6 https://doi.org/10.1002/jps.23548	journal	June 2013
Heat-separation of normal human skin for epidermal and dermal prostaglandin analysis Kassis, V.; S�ndergaard, J. Archives of Dermatological Research, Vol. 273-273, Issue 3-4 https://doi.org/10.1007/bf00409259	journal	July 1982
Correction of Perfusate Concentration for Sample Removal Hayton, William L.; Chen, Tina Journal of Pharmaceutical Sciences, Vol. 71, Issue 7 https://doi.org/10.1002/jps.2600710726	journal	July 1982
The UV-filter benzophenone-1 inhibits 17β-hydroxysteroid dehydrogenase type 3: Virtual screening as a strategy to identify potential endocrine disrupting chemicals Nashev, Lyubomir G.; Schuster, Daniela; Laggner, Christian Biochemical Pharmacology, Vol. 79, Issue 8 https://doi.org/10.1016/j.bcp.2009.12.005	journal	April 2010
Systemic Absorption of Sunscreen Adamson, Adewole S.; Shinkai, Kanade JAMA, Vol. 323, Issue 3 https://doi.org/10.1001/jama.2019.20143	journal	January 2020
Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients Matta, Murali K.; Zusterzeel, Robbert; Pilli, Nageswara R. JAMA, Vol. 321, Issue 21 https://doi.org/10.1001/jama.2019.5586	journal	June 2019
Effect of Sunscreen Application on Plasma Concentration of Sunscreen Active Ingredients Matta, Murali K.; Florian, Jeffry; Zusterzeel, Robbert JAMA, Vol. 323, Issue 3 https://doi.org/10.1001/jama.2019.20747	journal	January 2020
Concentrations of the Sunscreen Agent Benzophenone-3 in Residents of the United States: National Health and Nutrition Examination Survey 2003–2004 Calafat, Antonia M.; Wong, Lee-Yang; Ye, Xiaoyun Environmental Health Perspectives, Vol. 116, Issue 7 https://doi.org/10.1289/ehp.11269	journal	July 2008
Trans-resveratrol and beta-carotene from sunscreens penetrate viable skin layers and reduce cutaneous penetration of UV-filters Freitas, J. V.; Praça, F. S. G.; Bentley, M. V. L. B. International Journal of Pharmaceutics, Vol. 484, Issue 1-2 https://doi.org/10.1016/j.ijpharm.2015.02.062	journal	April 2015
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