Positron emission tomography (PET) for evaluating chest masses

Journal Article · Sun May 01 04:00:00 EDT 1994 · Journal of Nuclear Medicine

OSTI ID:198075

Hubner, K F; Smith, G T; Hunter, K ^[1]

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1. Univ. of Tennessee Medical Center, Knoxville, TN (United States); and others

Assessment of lung masses by CT is sensitive but non-specific for detecting malignancy. High resolution PET offers the unique opportunity to distinguish benign from malignant processes. The purpose of this retrospective study was to determine the accuracy of PET in (1) patients with undetermined lung masses (N=29),(2) patients with suspected pulmonary metastases from non-lung tumors (N=25). Minimum acceptable lesion size for this study was 1 cm by CT. PET F-18-FDG (5-10 mCi) data were acquired in dynamic scanning mode to facilitate time-activity-curve and graphical (Patlak) analysis. Standardized uptake values (SUV`s) were calculated for tumor and non-neoplastic tissue. Results were compared to histological findings and/or clinical outcome. Results of visual and SUV analysis, not including data from patients with breast cancer.

• OSTI ID: 198075
• Report Number(s): CONF-940605--
• Journal Information: Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: Suppl.5 Vol. 35; ISSN JNMEAQ; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
ACCURACY
FLUORINE 18
FLUORODEOXYGLUCOSE
LUNGS
METABOLISM
METASTASES
NEOPLASMS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RESOLUTION