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Genetic diversity loss in the Anthropocene

Journal Article · · Science
 [1];  [2];  [3];  [4];  [3];  [5];  [6];  [7];  [8];  [6];  [3];  [9];  [7];  [9];  [3]
  1. Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA.; Department of Biology, Stanford University, Stanford, CA 94305, USA.; Department of Global Ecology, Carnegie Institution for Science, Stanford, CA 94305, USA.
  2. Department of Zoology, University of British Columbia, Vancouver, Canada.; Biodiversity Research Centre, University of British Columbia, Vancouver, Canada.
  3. Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA.
  4. Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA.; Department of Computer Science, Stanford University, Stanford, CA 94305, USA.
  5. Department of Ecology and Evolutionary Biology, University of California, Los Angeles, CA 90095, USA.
  6. Department of Biology, Stanford University, Stanford, CA 94305, USA.
  7. Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA.; Department of Biology, Stanford University, Stanford, CA 94305, USA.
  8. Center for Macroecology, Evolution and Climate, GLOBE Institute, University of Copenhagen, Copenhagen, Denmark.
  9. Department of Genetics, Stanford University, Stanford, CA 94305, USA.

Anthropogenic habitat loss and climate change are reducing species’ geographic ranges, increasing extinction risk and losses of species’ genetic diversity. Although preserving genetic diversity is key to maintaining species’ adaptability, we lack predictive tools and global estimates of genetic diversity loss across ecosystems. We introduce a mathematical framework that bridges biodiversity theory and population genetics to understand the loss of naturally occurring DNA mutations with decreasing habitat. By analyzing genomic variation of 10,095 georeferenced individuals from 20 plant and animal species, we show that genome-wide diversity follows a mutations-area relationship power law with geographic area, which can predict genetic diversity loss from local population extinctions. We estimate that more than 10% of genetic diversity may already be lost for many threatened and nonthreatened species, surpassing the United Nations’ post-2020 targets for genetic preservation.

Research Organization:
Illinois State University (ISU), Normal, IL (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
SC0021286
OSTI ID:
1980743
Journal Information:
Science, Vol. 377, Issue 6613; ISSN 0036-8075
Publisher:
AAAS
Country of Publication:
United States
Language:
English

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