A comparison of functional MRI and H{sub 2}O-15 PET changes during visual stimulation
- Johns Hopkins Medical Inst., Baltimore, MD (United States); and others
To ascertain whether local changes in signal intensity seen with functional MRI (fMRI) were related to regional blood flow changes with PET, 45 normal male volunteers (ages 31-49) underwent both procedures during resting and bilateral visual stimulation. A single 4mm thick fMRI slice over the calcarine fissure was acquired with a gradient echo 60,60,40{prime} (TR,TE,{alpha}), on a GE Signa 1.5 T. Sixty images were acquired over 366 sec. The visual stimulator was turned on and off at intervals of 36 sec, with a stimulating frequency of 8 Hz. ROIs were drawn around clusters of pixels with high z-scores (pixel value-mean over whole acquisition/SD). Several ROIs were drawn in each subject. Percent change in signal intensity was calculated as the intensity in the average of six {open_quotes}on{close_quotes} images over the average of six {open_quotes}off{close_quotes} images 100.
- OSTI ID:
- 197905
- Report Number(s):
- CONF-940605-; ISSN 0161-5505; TRN: 95:007029-0031
- Journal Information:
- Journal of Nuclear Medicine, Vol. 35, Issue Suppl.5; Conference: 41. annual meeting of the Society of Nuclear Medicine, Orlando, FL (United States), 5-8 Jun 1994; Other Information: PBD: May 1994
- Country of Publication:
- United States
- Language:
- English
Similar Records
High spatial resolution brain functional MRI using submillimeter balanced steady-state free precession acquisition
Precision of repeated quantitative FDG-PET scans in patients with untreated lung cancer