TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response

Mondragon, Paula; Hwang, Sungmin; Kasirajan, Lakshmi; Oyetoro, Rebecca; Nasthas, Angelina; Winters, Emily; Couto-Rodriguez, Ricardo L.; Schmid, Amy; Maupin-Furlow, Julie A.; Babitzke, ed., Paul

doi:10.1128/mbio.00633-22

TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response

Journal Article · Tue Aug 30 00:00:00 EDT 2022 · mBio (Online)

DOI:https://doi.org/10.1128/mbio.00633-22· OSTI ID:1876919

Mondragon, Paula ^[1]; Hwang, Sungmin ^[2]; Kasirajan, Lakshmi ^[3]; Oyetoro, Rebecca ^[1]; Nasthas, Angelina ^[1]; Winters, Emily ^[1]; Couto-Rodriguez, Ricardo L. ^[1]; ^[4]; ^[5]; Babitzke, ed., Paul

Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA
Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA, Department of Biology, Duke University, Durham, North Carolina, USA
Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA, ICAR-Sugarcane Breeding Institute, Coimbatore, India
Department of Biology, Duke University, Durham, North Carolina, USA, Center for Genomics and Computational Biology, Duke University, Durham, North Carolina, USA
Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA, Genetics Institute, University of Florida, Gainesville, Florida, USA

TrmB-like proteins, while not yet associated with redox stress, are found in bacteria and widespread in archaea. Here, we expand annotation of a large group of TrmB-like single winged-helix DNA binding domain proteins from diverse archaea to function as thiol-based transcriptional regulators of oxidative stress response.

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Sponsoring Organization:: USDOE

OSTI ID:: 1876919

Alternate ID(s):: OSTI ID: 1904665

Journal Information:: mBio (Online), Journal Name: mBio (Online) Journal Issue: 4 Vol. 13; ISSN 2150-7511

Publisher:: American Society for MicrobiologyCopyright Statement

Country of Publication:: United States

Language:: English

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