Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Lo

He, Rongjun; Wang, Jifeng; Yu, Zhi-Hong; Moyers, Julie S.; Michael, M. Dodson; Durham, Timothy B.; Cramer, Jeff W.; Qian, Yuewei; Lin, Amy; Wu, Li; Noinaj, Nicholas; Barrett, David G.; Zhang, Zhong-Yin

doi:10.1021/acs.jmedchem.2c01143

Title: Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Lo

Journal Article · 01 October 2022 · J. Med. Chem.

DOI:https://doi.org/10.1021/acs.jmedchem.2c01143· OSTI ID:1901192

He, Rongjun; Wang, Jifeng; Yu, Zhi-Hong; Moyers, Julie S.; Michael, M. Dodson; Durham, Timothy B.; Cramer, Jeff W.; Qian, Yuewei; Lin, Amy; Wu, Li; Noinaj, Nicholas; Barrett, David G.; Zhang, Zhong-Yin

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: DOE - Office Of Science; INDUSTRY

OSTI ID:: 1901192

Journal Information:: J. Med. Chem., Vol. 65, Issue (20)

Country of Publication:: United States

Language:: ENGLISH

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