Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic

Liu, Jing; Yang, Chao; Simpson, Catherine; DeRyckere, Deborah; Van Deusen, Amy; Miley, Michael J.; Kireev, Dmitri; Norris-Drouin, Jacqueline; Sather, Susan; Hunter, Debra; Korboukh, Victoria K.; Patel, Hari S.; Janzen, William P.; Machius, Mischa; Johnson, Gary L.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong

doi:10.1021/ml200239k

Discovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic

Journal Article · Mon Dec 31 23:00:00 EST 1984 · ACS Med. Chem. Lett.

DOI:https://doi.org/10.1021/ml200239k· OSTI ID:1867449

Liu, Jing; Yang, Chao; Simpson, Catherine; DeRyckere, Deborah; Van Deusen, Amy; Miley, Michael J.; Kireev, Dmitri; Norris-Drouin, Jacqueline; Sather, Susan; Hunter, Debra; Korboukh, Victoria K.; Patel, Hari S.; Janzen, William P.; Machius, Mischa; Johnson, Gary L.; Earp, H. Shelton; Graham, Douglas K.; Frye, Stephen V.; Wang, Xiaodong

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: DOE - Office Of Science; UNIVERSITY

OSTI ID:: 1867449

Journal Information:: ACS Med. Chem. Lett., Journal Name: ACS Med. Chem. Lett. Journal Issue: (2) Vol. 3

Country of Publication:: United States

Language:: ENGLISH

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Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR) Kaplan, Joshua; Verheijen, Jeroen C.; Brooijmans, Natasja Bioorganic & Medicinal Chemistry Letters, Vol. 20, Issue 2 https://doi.org/10.1016/j.bmcl.2009.11.050	journal	January 2010
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