The genes encoding {alpha}2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4
- Harvard Medical School, Boston, MA (United States); and others
We have determined the chromosomal locations of the human and murine genes coding for {alpha}2(IX) collagen, a polypeptide subunit of the heterotrimeric type IX collagen molecule. COL9A2 was mapped to human chromosome 1p32.3-p33 using fluorescence in situ hybridization. A single-strand conformational polymorphism within the murine Col9a2 gene was used to map this locus to mouse chromosome 4. We also present new sequence data, which completes the coding information for the human {alpha}2(IX) chain. This permits comparison of the carboxyl-terminal (NC1) domains of the {alpha}1(IX), {alpha}2(IX), and {alpha}3(IX) chains across several species. 32 refs., 3 figs.
- OSTI ID:
- 186064
- Journal Information:
- Genomics, Vol. 23, Issue 1; Other Information: PBD: 1 Sep 1994
- Country of Publication:
- United States
- Language:
- English
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