The human CHC1 gene encoding RCC1 (regulator of chromosome condensation) (CHC1) is localized to human chromosome 1p36.1
- Kyushu Univ. Higashi-ku (Japan)
- National Institute of Radiological Science, Chiba (Japan)
- National Institute of Radiological Science, Chiba, (Japan)
The human CHC1 gene encoding RCC1 (regulator of chromosome condensation) encodes a chromosomal protein of 45 kDa that has seven internal homologous repeats and functions as a guanine nucleotide releasing factor on the nuclear Ras-like small G protein. We report here the precise localization of the RCC1 gene to human chromosome 1p36.1. There is a conserved region of homology between the 1p36 region of human and a distal region of mouse chromosome 4. Thus, the assignment of the human gene encoding RCC1 adds another marker to the conserved region of homology between human chromosome 1p and mouse chromosome 4. 17 refs., 1 fig.
- OSTI ID:
- 183714
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 3 Vol. 23; ISSN 0888-7543; ISSN GNMCEP
- Country of Publication:
- United States
- Language:
- English
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