Microscale wear behavior and crosslinking of PEG-like coatings for total hip replacements

Kane, Sheryl R.; Ashby, Paul D.; Pruitt, Lisa A.

doi:10.1007/s10856-009-3935-6

Microscale wear behavior and crosslinking of PEG-like coatings for total hip replacements

Journal Article · Sat Dec 19 23:00:00 EST 2009 · Journal of Materials Science: Materials in Medicine

DOI:https://doi.org/10.1007/s10856-009-3935-6· OSTI ID:1815739

Kane, Sheryl R. ^[1]; Ashby, Paul D. ^[2]; Pruitt, Lisa A. ^[3]

Univ. of California, Berkeley, CA (United States). Univ. of California, San Francisco. Joint Graduate Group in Bioengineering; OSTI
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Molecular Foundry
Univ. of California, Berkeley, CA (United States). Univ. of California, San Francisco. Joint Graduate Group in Bioengineering; Univ. of California, Berkeley, CA (United States). Mechanical Engineering

The predominant cause of late-state failure of total hip replacements is wear-mediated osteolysis caused by wear particles that originate from the ultrahigh molecular weight polyethylene (UHMWPE) acetabular cup surface. One strategy for reducing wear particle formation from UHMWPE is to modify the surface with a hydrophilic coating to increase lubrication from synovial fluid. This study focuses on the wear behavior of hydrophilic coatings similar to poly(ethylene glycol) (PEG). The coatings were produced by plasma-polymerizing tetraglyme on UHMWPE in a chamber heated to 40C or 50C. Both temperatures yielded coatings with PEG-like chemistry and increased hydrophilicity relative to uncoated UHMWPE; however, the 40C coatings were significantly more resistant to damage induced by atomic force microscopy nanoscratching. The 40C coatings exhibited only one damage mode (delamination) and often showed no signs of damage after repeated scratching. In contrast, the 50C coatings exhibited three damage modes (roughening, thinning, and delamination), and always showed visible signs of damage after no more than two scratches. The greater wear resistance of the 40C coatings could not be explained by coating chemistry or hydrophilicity, but it corresponded to an approximately 26–32% greater degree of crosslinking relative to the 50C surfaces, suggesting that crosslinking should be a significant design consideration for hydrophilic coatings used for total hip replacements and other wear-dependent applications.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division; National Science Foundation (NSF); National Institutes of Health (NIH)

Grant/Contract Number:: AC02-05CH11231

OSTI ID:: 1815739

Journal Information:: Journal of Materials Science: Materials in Medicine, Journal Name: Journal of Materials Science: Materials in Medicine Journal Issue: 4 Vol. 21; ISSN 0957-4530

Publisher:: Springer NatureCopyright Statement

Country of Publication:: United States

Language:: English

References (21)

The effects of degree of crosslinking on the fatigue crack initiation and propagation resistance of orthopedic-grade polyethylene Baker, D. A.; Bellare, A.; Pruitt, L. Journal of Biomedical Materials Research, Vol. 66A, Issue 1 https://doi.org/10.1002/jbm.a.10606	journal	June 2003
A novel ultra high molecular weight polyethylene–hyaluronan microcomposite for use in total joint replacements. II. Mechanical and tribological property evaluation Zhang, Min; Pare, Philippe; King, Richard Journal of Biomedical Materials Research Part A, Vol. 82A, Issue 1 https://doi.org/10.1002/jbm.a.31141	journal	January 2007
Wear reduction of orthopaedic bearing surfaces using polyelectrolyte multilayer nanocoatings Pavoor, Prem V.; Gearing, Brian P.; Muratoglu, Orhun Biomaterials, Vol. 27, Issue 8 https://doi.org/10.1016/j.biomaterials.2005.08.022	journal	March 2006
Study on the tribological properties of pHEMA hydrogels for use in artificial articular cartilage Bavaresco, V. P.; Zavaglia, C. A. C.; Reis, M. C. Wear, Vol. 265, Issue 3-4 https://doi.org/10.1016/j.wear.2007.10.009	journal	July 2008
Friction, wear, and lubrication of hydrogels as synthetic articular cartilage Freeman, Mark E.; Furey, Michael J.; Love, Brian J. Wear, Vol. 241, Issue 2 https://doi.org/10.1016/s0043-1648(00)00387-2	journal	July 2000
Unified wear model for highly crosslinked ultra-high molecular weight polyethylenes (UHMWPE) Muratoglu, Orhun K.; Bragdon, Charles R.; O’Connor, Daniel O. Biomaterials, Vol. 20, Issue 16 https://doi.org/10.1016/s0142-9612(99)00039-3	journal	August 1999
Advances in the processing, sterilization, and crosslinking of ultra-high molecular weight polyethylene for total joint arthroplasty Kurtz, S. Biomaterials, Vol. 20, Issue 18 https://doi.org/10.1016/s0142-9612(99)00053-8	journal	September 1999
Plasma Deposition and Surface Characterization of Oligoglyme, Dioxane, and Crown Ether Nonfouling Films Johnston, Erika E.; Bryers, James D.; Ratner, Buddy D. Langmuir, Vol. 21, Issue 3 https://doi.org/10.1021/la036274s	journal	December 2004
Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis Moro, Toru; Takatori, Yoshio; Ishihara, Kazuhiko Nature Materials, Vol. 3, Issue 11 https://doi.org/10.1038/nmat1233	journal	October 2004
Comparison of Cross-Linked Polyethylene Materials for Orthopaedic Applications Collier, John P.; Currier, Barbara H.; Kennedy, Francis E. Clinical Orthopaedics and Related Research, Vol. 414 https://doi.org/10.1097/01.blo.0000073343.50837.03	journal	January 2003
Tribological and Nanomechanical Properties of Unmodified and Crosslinked Ultra-High Molecular Weight Polyethylene for Total Joint Replacements Zhou, J.; Chakravartula, A.; Pruitt, L. Journal of Tribology, Vol. 126, Issue 2 https://doi.org/10.1115/1.1611511	journal	April 2004
Biological reactions to wear debris in total joint replacement Ingham, E.; Fisher, J. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Vol. 214, Issue 1 https://doi.org/10.1243/0954411001535219	journal	January 2000
The Basic Science of Periprosthetic Osteolysis*† Archibeck, Michael J.; Jacobs, Joshua J.; Roebuck, Kenneth A. The Journal of Bone and Joint Surgery-American Volume, Vol. 82, Issue 10 https://doi.org/10.2106/00004623-200010000-00014	journal	January 2000
Characterization and tribology of PEG-like coatings on UHMWPE for total hip replacements Kane, Sheryl R.; Ashby, Paul D.; Pruitt, Lisa A. Journal of Biomedical Materials Research Part A, Vol. 9999A https://doi.org/10.1002/jbm.a.32484	journal	January 2009
ATR-FTIR as a thickness measurement technique for hydrated polymer-on-polymer coatings Kane, Sheryl R.; Ashby, Paul D.; Pruitt, Lisa A. Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 91B, Issue 2 https://doi.org/10.1002/jbm.b.31436	journal	November 2009
Friction, wear, and lubrication of hydrogels as synthetic articular cartilage Freeman, Mark E.; Furey, Michael J.; Love, Brian J. Wear, Vol. 241, Issue 2 https://doi.org/10.1016/S0043-1648(00)00387-2	journal	July 2000
Unified wear model for highly crosslinked ultra-high molecular weight polyethylenes (UHMWPE) Muratoglu, Orhun K.; Bragdon, Charles R.; O’Connor, Daniel O. Biomaterials, Vol. 20, Issue 16 https://doi.org/10.1016/S0142-9612(99)00039-3	journal	August 1999
Advances in the processing, sterilization, and crosslinking of ultra-high molecular weight polyethylene for total joint arthroplasty Kurtz, S. Biomaterials, Vol. 20, Issue 18 https://doi.org/10.1016/S0142-9612(99)00053-8	journal	September 1999
Particle bioreactivity and wear-mediated osteolysis Wang, Mark L.; Sharkey, Peter F.; Tuan, Rocky S. The Journal of Arthroplasty, Vol. 19, Issue 8 https://doi.org/10.1016/j.arth.2004.03.024	journal	December 2004
Statistical Mechanics of Cross‐Linked Polymer Networks II. Swelling Flory, Paul J.; Rehner, John The Journal of Chemical Physics, Vol. 11, Issue 11 https://doi.org/10.1063/1.1723792	journal	November 1943
Mechanistic and Morphological Origins of Ultra-High Molecular Weight Polyethylene Wear Debris in Total Joint Replacement Prostheses Wang, A.; Stark, C.; Dumbleton, J. H. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Vol. 210, Issue 3 https://doi.org/10.1243/PIME_PROC_1996_210_407_02	journal	September 1996

Similar Records

Tensile and tribological properties of high-crystallinity radiation crosslinked UHMWPE

Journal Article · Wed Sep 02 00:00:00 EDT 2009 · J. Biomed. Mater. Res.-B · OSTI ID:1005809

Tribological studies of a novel high-performance aromatic thermosetting copolyester containing carbon nanotubes for artificial hip joints

Journal Article · Fri Nov 04 00:00:00 EDT 2022 · Tribology International · OSTI ID:2419379

Computed tomography in congenital hip dislocation. The role of acetabular anteversion

Journal Article · Thu Dec 31 23:00:00 EST 1981 · J. Bone Jt. Surg., Am. Vol.; (United States) · OSTI ID:5368103

Related Subjects

36 MATERIALS SCIENCE
42 ENGINEERING
Atomic force microscopy
Crosslink density
UHMWPE
Ultrahigh molecular weight polyethylene
Wear behavior

Microscale wear behavior and crosslinking of PEG-like coatings for total hip replacements

Citation Formats

References (21)

Similar Records

Related Subjects