Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia

Dieck, C; Tzoneva, G.; Forouhar, F.; Carpenter, Z.; Ambesi-Impiombato, A.; Sánchez-Martín, M.; Kirschner-Schwabe, R.; Lew, S.; Seetharaman, J.; Tong, L.; Ferrando, A.

doi:10.1016/j.ccell.2018.06.003

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia

Journal Article · Fri Dec 31 23:00:00 EST 2021 · Cancer Cell

DOI:https://doi.org/10.1016/j.ccell.2018.06.003· OSTI ID:1783959

Dieck, C; Tzoneva, G.; Forouhar, F.; Carpenter, Z.; Ambesi-Impiombato, A.; Sánchez-Martín, M.; Kirschner-Schwabe, R.; Lew, S.; Seetharaman, J.; Tong, L.; Ferrando, A.

Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: ~OTHER

DOE Contract Number:: SC0012704

OSTI ID:: 1783959

Report Number(s):: BNL-221490-2021-JACI

Journal Information:: Cancer Cell, Journal Name: Cancer Cell Journal Issue: 1 Vol. 34; ISSN 1535-6108

Country of Publication:: United States

Language:: English

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Expanding the clinical relevance of the 5′-nucleotidase cN-II/NT5C2 Jordheim, Lars Petter Purinergic Signalling, Vol. 14, Issue 4 https://doi.org/10.1007/s11302-018-9627-2	journal	October 2018
Genetics and mechanisms of NT5C2-driven chemotherapy resistance in relapsed ALL Dieck, Chelsea L.; Ferrando, Adolfo Blood, Vol. 133, Issue 21 https://doi.org/10.1182/blood-2019-01-852392	journal	May 2019
Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia Li, Benshang; Brady, Samuel W.; Ma, Xiaotu Blood, Vol. 135, Issue 1 https://doi.org/10.1182/blood.2019002220	journal	January 2020
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics Koczian, Fabian; Nagło, Olga; Vomacka, Jan Haematologica, Vol. 104, Issue 3 https://doi.org/10.3324/haematol.2018.197368	journal	October 2018
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