Emesis in ferrets following exposure to different types of radiation: A dose-response study. (Reannouncement with new availability information)
Technical Report
·
OSTI ID:177490
Ferrets were exposed to gamma rays (60Co), fission neutrons, high-energy electrons (18.5 MeV) or iron particles (56Fe, 600 MeV/amu) in order to establish the dose-response relationships for emesis following exposure to different types of radiation. The results showed that the mean effective doses (ED50s) for iron particles (35 cGy) and neutrons (40 cGy) were similar. High energy electrons were the least effective radiation, with an ED50 of 138 cGy. Gamma rays, with an ED50 of 95 cGy, showed an intermediate effectiveness. The results suggest that the relative effectiveness of different types of radiation generally increases with an increase in linear energy transfer (LET), although LET is not completely predictive of relative behavioral effectiveness.
- Research Organization:
- Armed Forces Radiobiology Research Inst., Bethesda, MD (United States)
- OSTI ID:
- 177490
- Report Number(s):
- AD-A--257408/5/XAB; AFRRI-SR--92-34
- Country of Publication:
- United States
- Language:
- English
Similar Records
Characterization of radiation-induced emesis in the ferret
Characterization of radiation-induced emesis in the ferret
Is all radiation-induced emesis ameliorated by 5-HT3 receptor antagonists. (Reannouncement with new availability information)
Journal Article
·
Wed Jun 01 00:00:00 EDT 1988
· Radiat. Res.; (United States)
·
OSTI ID:6922585
Characterization of radiation-induced emesis in the ferret
Technical Report
·
Thu Dec 31 23:00:00 EST 1987
·
OSTI ID:5715585
Is all radiation-induced emesis ameliorated by 5-HT3 receptor antagonists. (Reannouncement with new availability information)
Technical Report
·
Wed Dec 30 23:00:00 EST 1992
·
OSTI ID:177489