Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway

Fischer, Curt R.; Che, Austin J.; Shetty, Reshma P.; Kelly, Jason R.

Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway

Patent · 13 October 2020

OSTI ID:1771496

Fischer, Curt R.; Che, Austin J.; Shetty, Reshma P.; Kelly, Jason R.

The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.

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Research Organization:: Gingko Bioworks, Inc., Boston, MA (United States)

Sponsoring Organization:: USDOE Advanced Research Projects Agency - Energy (ARPA-E)

DOE Contract Number:: AR0000091

Assignee:: Ginkgo Bioworks, Inc. (Boston, MA)

Patent Number(s):: 10,801,045

Application Number:: 15/867,209

OSTI ID:: 1771496

Country of Publication:: United States

Language:: English

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