Multi-organ media compositions and methods of their use
Disclosed herein are media for culture of cells, tissues, and/or organs. The media formulations disclosed herein can be used to support growth, viability, and/or function of one or more than one cell type, tissue, or organ. In some embodiments, one or more cell types, tissues, organ devices, and/or organs are contacted with a disclosed culture medium under conditions sufficient to support growth, viability, and/or function of the cell types, tissues, and/or organs. The disclosed media can be used in methods of culturing multiple cell types, and in some examples, is used in a platform device including one or more organ devices, for example, by circulating the medium through the one or more organ devices in the platform.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC52-06NA25396
- Assignee:
- Triad National Security, LLC (Los Alamos, NM); CFD Research Corporation (Huntsville, AL)
- Patent Number(s):
- 10,564,148
- Application Number:
- 15/513,948
- OSTI ID:
- 1632572
- Resource Relation:
- Patent File Date: 09/24/2015
- Country of Publication:
- United States
- Language:
- English
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