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Title: International pooled study on diet and bladder cancer: the bladder cancer, epidemiology and nutritional determinants (BLEND) study: design and baseline characteristics

Journal Article · · Archives of Public Health
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  1. Katholieke Univ. Leuven, Heverlee (Belgium). Dept. of General Practice
  2. Univ. of Birmingham (United Kingdom). Dept. of Public Health, Epidemiology and Biostatistics
  3. The Cancer Council Victoria, Melbourne (Australia)
  4. University of Maastricht (Netherlands). NUTRIM School for Nutrition and Translational Research in Metabolism
  5. Fondation Jean Dausset / CEPH, Paris (France). Variabilite Genetique et Maladies Humaines. INSERM
  6. Istituto di Ricerche Farmacologiche “Mario Negri”, Milan (Italy). Lab. of General Epidemiology
  7. National Inst. for Public Health and the Environment (RIVM), Bilthoven (Netherlands). Determinants of Chronic Diseases (DCD); Univ. Medical Centre, Utrecht (Netherlands). Gastroenterology and Hepatology; Imperial College, London (United Kingdom). The School of Public Health. Epidemiology and Biostatistics; Univ. of Malaya, Kuala Lumpur (Malaysia). Scoial and Preventive Medicine
  8. Univ. of Brescia (Italy). Section of Public Health and Human Sciences. Radiological Sciences and Public Health. Dept. of Medical and Surgical Specialties
  9. University of Cordoba, (Spain). Faculty of Medicine. Dept. of Preventive Medicine and Public Health
  10. Technische Univ. of Dortmund (Germany). Leibniz Research Centre for Working Environment and Human Factors
  11. Dept. of Epidemiology Radiation Effects Research Foundation, Hiroshima (Japan)
  12. Univ. of Southern California, Los Angeles, CA (United States). Dept. of Preventive Medicine
  13. Univ. of Ottawa, ON (Canada). Dept. of Epidemiology and Community Medicine
  14. Dartmouth College, Hanover, NH (United States). Geisel School of Medicine. Dept. of Epidemiology
  15. Leuven Univ. Centre for Cancer Prevention (LUCK), Lueven (Belgium)
  16. Univ. of Milan (Italy). Dept. of Clinical Medicine and Community Health
  17. Buddhist Dalin Tzu Chi General Hospital, Chiayi County (Taiwan). Dept. of Urology
  18. Roswell Park Cancer Institute, Buffalo, NY (United States). Dept. of Cancer Prevention and Control
  19. Leibniz Inst. for Prevention Research and Epidemiology – BIPS, Bremen (Germany)
  20. Karolinska Hospital, Stockholm (Sweden). Division of Clinical Cancer Epidemiology. Dept. of Oncology and Pathology
  21. National Institutes of Health (NIH), Research Triangle Park, NC (United States). National Inst. of Environmental Health Sciences. Epidemiology Branch. Epigenetic and Stem Cell Biology Lab.
  22. Maastricht University Medical Centre, Maastricht (Netherlands). Schools Oncology and Developmental Biology and Public Health and Primary Care. Dept. of Epidemiology
  23. Population Studies Division Health Canada, Ottawa, ON (Canada)
  24. Nagoya Univ. (Japan). Graduate School of Medicine. Dept. of Preventive Medicine
  25. Karolinska Institutet, Stockholm (Sweden). Medical Epidemiology. Dept. of Medical Epidemiology and Biostatistics; Cancer Registry of Norway, Oslo (Norway). Inst. of Population-Based Cancer Research. Dept. of Research; Folkhälsan Research Center, Helsinki (Finland). Genetic Epidemiology Group; The Arctic University of Norway, Tromsø (Norway). Univ. of Tromsø. Dept. of Community Medicine
  26. Fred Hutchinson Cancer Research Center, Seattle, WA (United States)
  27. Karolinska Institutet, Stockholm (Sweden). Inst. of Environmental Medicine. Division of Nutritional Epidemiology
  28. Univ. of California, Los Angeles, CA (United States). Fielding School of Public Health. UCLA Center for Environmental Genomics. Dept. of Epidemiology
  29. Katholieke Univ. Leuven, Heverlee (Belgium). Dept. of General Practice; Univ. of Maastricht (Netherlands). CAPHRI School for Public Health and Primary Care
  30. University of Maastricht (Netherlands). NUTRIM School for Nutrition and Translational Research in Metabolism; niv. of Maastricht (Netherlands). CAPHRI School for Public Health and Primary Care; Univ. of Birmingham (United Kingdom). School of Cancer Sciences
+ Show Author Affiliations

Background: In 2012, more than 400,000 urinary bladder cancer cases occurred worldwide, making it the 7th most common type of cancer. Although many previous studies focused on the relationship between diet and bladder cancer, the evidence related to specific food items or nutrients that could be involved in the development of bladder cancer remains inconclusive. Dietary components can either be, or be activated into, potential carcinogens through metabolism, or act to prevent carcinogen damage. Methods/design: The BLadder cancer, Epidemiology and Nutritional Determinants (BLEND) study was set up with the purpose of collecting individual patient data from observational studies on diet and bladder cancer. In total, data from 11,261 bladder cancer cases and 675,532 non-cases from 18 case–control and 6 cohort studies from all over the world were included with the aim to investigate the association between individual food items, nutrients and dietary patterns and risk of developing bladder cancer. Discussion: The substantial number of cases included in this study will enable us to provide evidence with large statistical power, for dietary recommendations on the prevention of bladder cancer.

Research Organization:
Univ. of Southern California, Los Angeles, CA (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Biological and Environmental Research (BER). Biological Systems Science Division; Bundesanstalt fur Arbeitsschutz; Nation Scientific Council of the Republic of China; National Cancer Institute (NCI); National Institutes of Health (NIH)
Grant/Contract Number:
HS0000031; F 1287; NSC 85-2332-B-037-066; CA11535; CA16056; 5 P42 ES007373; 94.01321.PF39; 94.01119.PF39; ES06718; U01 CA96116; CA09142
OSTI ID:
1629714
Journal Information:
Archives of Public Health, Vol. 74, Issue 1; ISSN 2049-3258
Publisher:
BioMed CentralCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (5)

An inverse association between the Mediterranean diet and bladder cancer risk: a pooled analysis of 13 cohort studies journal February 2019
The association between coffee consumption and bladder cancer in the bladder cancer epidemiology and nutritional determinants (BLEND) international pooled study journal May 2019
Intake of milk and other dairy products and the risk of bladder cancer: a pooled analysis of 13 cohort studies journal June 2019
Differences in Pathologic Results of Repeat Transurethral Resection of Bladder Tumor (TURBT) according to Institution Performing the Initial TURBT: Comparative Analyses between Referred and Nonreferred Group journal September 2018
Coffee consumption and risk of bladder cancer: a pooled analysis of 501,604 participants from 12 cohort studies in the BLadder Cancer Epidemiology and Nutritional Determinants (BLEND) international study journal January 2020

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Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES
Bladder cancer
Diet
Risk
Pooled analysis