Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes

doi:https://doi.org/10.3390/nano10030571

Title: Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes

Abstract

Synthetic membranes containing asymmetrically shaped pores have been shown to rectify the ionic current flowing through the membrane. Ion-current rectification means that such membranes produce nonlinear current–voltage curves analogous to those observed with solid-state diode rectifiers. In order to observe this ion-current rectification phenomenon, the asymmetrically shaped pores must have pore-wall surface charge. Pore-wall surface charge also allows for electroosmotic flow (EOF) to occur through the membrane. We have shown that, because ion-current is rectified, EOF is likewise rectified in such membranes. This means that flow through the membrane depends on the polarity of the voltage applied across the membrane, one polarity producing a higher, and the opposite producing a lower, flow rate. As is reviewed here, these ion-current and EOF rectification phenomena are being used to develop new sensing technologies. Results obtained from an ion-current-based sensor for hydrophobic cations are reviewed. In addition, ion-current and EOF rectification can be combined to make a new type of device—a chemoresponsive nanofluidic pump. This is a pump that either turns flow on or turns flow off, when a specific chemical species is detected. Results from a prototype Pb2+ chemoresponsive pump are also reviewed here.

Authors:

; Volta, Thomas T.;

Publication Date:: 2020-03-21

Sponsoring Org.:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

OSTI Identifier:: 1605947

Grant/Contract Number:: DESC0001160; SC0019112

Resource Type:: Journal Article: Published Article

Journal Name:: Nanomaterials

Additional Journal Information:: Journal Name: Nanomaterials Journal Volume: 10 Journal Issue: 3; Journal ID: ISSN 2079-4991

Publisher:: MDPI AG

Country of Publication:: Switzerland

Language:: English

Citation Formats


                    Bush, Stevie N., Volta, Thomas T., and Martin, Charles R. Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes.  Switzerland: N. p., 2020. 
        Web.  doi:10.3390/nano10030571.

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                    Bush, Stevie N., Volta, Thomas T., & Martin, Charles R. Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes.  Switzerland.  https://doi.org/10.3390/nano10030571

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                    Bush, Stevie N., Volta, Thomas T., and Martin, Charles R. Sat .  
        "Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes".  Switzerland.  https://doi.org/10.3390/nano10030571.

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@article{osti_1605947,

  title        = {Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes},

  author       = {Bush, Stevie N. and Volta, Thomas T. and Martin, Charles R.},

  abstractNote = {Synthetic membranes containing asymmetrically shaped pores have been shown to rectify the ionic current flowing through the membrane. Ion-current rectification means that such membranes produce nonlinear current–voltage curves analogous to those observed with solid-state diode rectifiers. In order to observe this ion-current rectification phenomenon, the asymmetrically shaped pores must have pore-wall surface charge. Pore-wall surface charge also allows for electroosmotic flow (EOF) to occur through the membrane. We have shown that, because ion-current is rectified, EOF is likewise rectified in such membranes. This means that flow through the membrane depends on the polarity of the voltage applied across the membrane, one polarity producing a higher, and the opposite producing a lower, flow rate. As is reviewed here, these ion-current and EOF rectification phenomena are being used to develop new sensing technologies. Results obtained from an ion-current-based sensor for hydrophobic cations are reviewed. In addition, ion-current and EOF rectification can be combined to make a new type of device—a chemoresponsive nanofluidic pump. This is a pump that either turns flow on or turns flow off, when a specific chemical species is detected. Results from a prototype Pb2+ chemoresponsive pump are also reviewed here.},

  doi          = {10.3390/nano10030571},

  url          = {https://www.osti.gov/biblio/1605947},
  journal      = {Nanomaterials},

  issn         = {2079-4991},

  number       = 3,

  volume       = 10,

  place        = {Switzerland},

  year         = {2020},

  month        = {3}

}

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Title: Chemical Sensing and Chemoresponsive Pumping with Conical-Pore Polymeric Membranes

Abstract

Citation Formats

Effect of Conical Nanopore Diameter on Ion Current Rectification journal, December 2009

An Alternating Current Electroosmotic Pump Based on Conical Nanopore Membranes journal, April 2016

Electrokinetic Flow in Ultrafine Capillary Slits 1 journal, May 1964

Electroosmotic Flow in Template-Prepared Carbon Nanotube Membranes journal, December 2001

Electrolysis-reducing electrodes for electrokinetic devices journal, March 2011

Track etching technique in membrane technology journal, June 2001

Microfluidic capture and release of bacteria in a conical nanopore array journal, January 2012

A zeta-potential model for ionic surfactant adsorption on an ionogenic hydrophobic surface journal, October 1988

Nanofluidics in Lab-on-a-Chip Devices journal, September 2009

Ion-Current Rectification in Nanopores and Nanotubes with Broken Symmetry journal, April 2006

Electrokinetic Flow in a Narrow Cylindrical Capillary journal, November 1965

Electroosmotic pumps and their applications in microfluidic systems journal, January 2009

Chemoresponsive Nanofluidic Pump That Turns Off in the Presence of Lead Ion journal, May 2018

Pore structure and function of synthetic nanopores with fixed charges: tip shape and rectification properties journal, June 2008

Probing Single DNA Molecule Transport Using Fabricated Nanopores journal, November 2004

The Role of Nanopore Geometry for the Rectification of Ionic Currents journal, March 2011

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Conical Nanopore Membranes. Preparation and Transport Properties journal, April 2004

Adsorption of surfactants and polymers at the solid-liquid interface journal, May 1997

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Fundamental Studies of Nanofluidics: Nanopores, Nanochannels, and Nanopipets journal, December 2014

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Resistive-Pulse DNA Detection with a Conical Nanopore Sensor † journal, December 2006

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Production and use of nuclear tracks: imprinting structure on solids journal, October 1983

Electric-field-induced wetting and dewetting in single hydrophobic nanopores journal, October 2011

Current Rectification at Quartz Nanopipet Electrodes journal, November 1997

A new drug-sensing paradigm based on ion-current rectification in a conically shaped nanopore journal, February 2008

Fabrication and Evaluation of Nanoelectrode Ensembles journal, July 1995

Conical Nanopore Membranes: Controlling the Nanopore Shape journal, February 2006

The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG) journal, January 1988

Calorimetric titration study of the interaction of several uni- and bivalent cations with 15-crown-5, 18-crown-6, and two isomers of dicyclohexo-18-crown-6 in aqueous solution at 25.degree.C and .mu. = 0.1 journal, November 1976

Electroosmotic Flow Rectification in Membranes with Asymmetrically Shaped Pores: Effects of Current and Pore Density journal, July 2015

Surface charge density of the track-etched nanopores in polyethylene terephthalate foils journal, June 2009

Nanofluidics in point of care applications journal, January 2014

Gated transport in nanofluidic devices journal, April 2011

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Kinetic studies of complexation of divalent strontium, barium, lead and mercury cations by aqueous 15-crown-5 and 18-crown-6 journal, March 1978

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Conical nanopore membranes: solvent shaping of nanopores journal, July 2006

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Developing synthetic conical nanopores for biosensing applications journal, January 2007

Ion separation in nanofluidics journal, September 2008

Lead-Selective Membrane Electrode Based on Dibenzopyrydino-18-Crown-6 journal, October 1996

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journal, May 1964

Electroosmotic Flow in Template-Prepared Carbon Nanotube Membranes
journal, December 2001

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Track etching technique in membrane technology
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Microfluidic capture and release of bacteria in a conical nanopore array
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A zeta-potential model for ionic surfactant adsorption on an ionogenic hydrophobic surface
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Ion transport through asymmetric nanopores prepared by ion track etching
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Resistive-Pulse DNA Detection with a Conical Nanopore Sensor ^†
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journal, December 2007

Production and use of nuclear tracks: imprinting structure on solids
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Electric-field-induced wetting and dewetting in single hydrophobic nanopores
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Current Rectification at Quartz Nanopipet Electrodes
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A new drug-sensing paradigm based on ion-current rectification in a conically shaped nanopore
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Fabrication and Evaluation of Nanoelectrode Ensembles
journal, July 1995

Conical Nanopore Membranes: Controlling the Nanopore Shape
journal, February 2006

The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG)
journal, January 1988

Calorimetric titration study of the interaction of several uni- and bivalent cations with 15-crown-5, 18-crown-6, and two isomers of dicyclohexo-18-crown-6 in aqueous solution at 25.degree.C and .mu. = 0.1
journal, November 1976

Electroosmotic Flow Rectification in Membranes with Asymmetrically Shaped Pores: Effects of Current and Pore Density
journal, July 2015

Surface charge density of the track-etched nanopores in polyethylene terephthalate foils
journal, June 2009

Nanofluidics in point of care applications
journal, January 2014

Gated transport in nanofluidic devices
journal, April 2011

Streaming Potential in Cylindrical Pores of Poly(ethylene terephthalate) Track-Etched Membranes: Variation of Apparent ζ Potential with Pore Radius
journal, May 2005

Electroosmotic Flow Rectification in Pyramidal-Pore Mica Membranes
journal, February 2010

Effect of Crown Ether on Ion Currents through Synthetic Membranes Containing a Single Conically Shaped Nanopore
journal, October 2005

Ionic Transport Phenomena in Nanofluidics: Experimental and Theoretical Study of the Exclusion-Enrichment Effect on a Chip
journal, June 2005

Conical-Nanotube Ion-Current Rectifiers: The Role of Surface Charge
journal, September 2004

Isoporous Micro/Nanoengineered Membranes
journal, March 2013

Kinetic studies of complexation of divalent strontium, barium, lead and mercury cations by aqueous 15-crown-5 and 18-crown-6
journal, March 1978

Effect of nanopore geometry on ion current rectification
journal, March 2011

Conical nanopore membranes: solvent shaping of nanopores
journal, July 2006

Rectification properties of conically shaped nanopores: consequences of miniaturization
journal, January 2013

Developing synthetic conical nanopores for biosensing applications
journal, January 2007

Ion separation in nanofluidics
journal, September 2008

Lead-Selective Membrane Electrode Based on Dibenzopyrydino-18-Crown-6
journal, October 1996