Identification of [ ¹⁸ F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

Journal Article · Fri Jan 05 04:00:00 EST 2018 · Journal of Medicinal Chemistry

DOI:https://doi.org/10.1021/acs.jmedchem.7b01607· OSTI ID:1539145

Bernard-Gauthier, Vadim ^[1]; Mossine, Andrew V. ^[2]; Mahringer, Anne ^[3]; Aliaga, Arturo ^[4]; Bailey, Justin J. ^[5]; Shao, Xia ^[2]; Stauff, Jenelle ^[2]; Arteaga, Janna ^[2]; Sherman, Phillip ^[2]; Grand’Maison, Marilyn ^[6]; Rochon, Pierre-Luc ^[7]; Wängler, Björn; Wängler, Carmen; Bartenstein, Peter ^[8]; Kostikov, Alexey ^[7]; Kaplan, David R. ^[9]; Fricker, Gert ^[3]; Rosa-Neto, Pedro ^[4]; Scott, Peter J. H. ^[10]; Schirrmacher, Ralf ^[5]

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1. Department of Oncology, Division of Oncological Imaging, University of Alberta, Edmonton, AB T6G 2R3, Canada; DOE/OSTI
2. Department of Radiology, Division of Nuclear Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, United States
3. Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg 69120, Germany
4. Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, Douglas Mental Health University Institute, Montreal, QC H4H 1R3, Canada
5. Department of Oncology, Division of Oncological Imaging, University of Alberta, Edmonton, AB T6G 2R3, Canada
6. Biospective Inc., Montreal, QC H4P 2R2, Canada
7. McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada
8. Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Munich 81377, Germany
9. Program in Neurosciences and Mental Health, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada
10. Department of Radiology, Division of Nuclear Medicine, The University of Michigan Medical School, Ann Arbor, Michigan 48109, United States; The Interdepartmental Program in Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States

Not provided.

• Research Organization: Univ. of Michigan, Ann Arbor, MI (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: SC0012484
• OSTI ID: 1539145
• Journal Information: Journal of Medicinal Chemistry, Journal Name: Journal of Medicinal Chemistry Journal Issue: 4 Vol. 61; ISSN 0022-2623
• Publisher: American Chemical Society (ACS)
• Country of Publication: United States
• Language: English

Related Subjects

Pharmacology & Pharmacy