Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

Kapraun, Dustin F.; Wambaugh, John F.; Setzer, R. Woodrow; Judson, Richard S.; Spradley, ed., Frank T.

doi:10.1371/journal.pone.0215906

Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

Journal Article · Thu May 02 00:00:00 EDT 2019 · PLoS ONE

DOI:https://doi.org/10.1371/journal.pone.0215906· OSTI ID:1510374

; ; ; ; Spradley, ed., Frank T.

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Research Organization:: Oak Ridge Inst. for Science and Education (ORISE), Oak Ridge, TN (United States)

Sponsoring Organization:: US Environmental Protection Agency (EPA); USDOE; USDOE Office of Science (SC)

Grant/Contract Number:: SC0014664

OSTI ID:: 1510374

Alternate ID(s):: OSTI ID: 1904972

Journal Information:: PLoS ONE, Journal Name: PLoS ONE Journal Issue: 5 Vol. 14; ISSN 1932-6203

Publisher:: Public Library of Science (PLoS)Copyright Statement

Country of Publication:: United States

Language:: English

References (36)

Evaluation of physiologically based pharmacokinetic models for use in risk assessment Chiu, Weihsueh A.; Barton, Hugh A.; DeWoskin, Robert S. Journal of Applied Toxicology, Vol. 27, Issue 3 https://doi.org/10.1002/jat.1225	journal	January 2007
A physiologically based pharmacokinetic computer model for human pregnancy Luecke, Richard H.; Wosilait, Walter D.; Pearce, Bruce A. Teratology, Vol. 49, Issue 2 https://doi.org/10.1002/tera.1420490205	journal	February 1994
Fetal cardiac output, distribution to the placenta and impact of placental compromise Kiserud, T.; Ebbing, C.; Kessler, J. Ultrasound in Obstetrics and Gynecology, Vol. 28, Issue 2 https://doi.org/10.1002/uog.2832	journal	January 2006
Evolution of Science-Based Uncertainty Factors in Noncancer Risk Assessment Dourson, Michael L.; Felter, Susan P.; Robinson, Denise Regulatory Toxicology and Pharmacology, Vol. 24, Issue 2 https://doi.org/10.1006/rtph.1996.0116	journal	October 1996
Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy Dallmann, André; Ince, Ibrahim; Meyer, Michaela Clinical Pharmacokinetics, Vol. 56, Issue 11 https://doi.org/10.1007/s40262-017-0539-z	journal	April 2017
Plasma volume and extravascular fluid volume during pregnancy and the puerperium Caton, William L.; Roby, Charles C.; Reid, Duncan E. American Journal of Obstetrics and Gynecology, Vol. 57, Issue 3 https://doi.org/10.1016/0002-9378(49)90232-X	journal	March 1949
Blood volume adjustments in the normal obstetric patient with particular reference to the third trimester of pregnancy Low, J. A.; Johnston, E. E.; McBride, R. L. American Journal of Obstetrics and Gynecology, Vol. 91, Issue 3 https://doi.org/10.1016/0002-9378(65)90250-4	journal	February 1965
Mathematical representation of organ growth in the human embryo/fetus Luecke, Richard H.; Wosilait, Walter D.; Young, John F. International Journal of Bio-Medical Computing, Vol. 39, Issue 3 https://doi.org/10.1016/0020-7101(95)01115-U	journal	June 1995
Blood flow and the degree of shunting through the ductus venosus in the human fetus Kiserud, Torvid; Rasmussen, Svein; Skulstad, Svein American Journal of Obstetrics and Gynecology, Vol. 182, Issue 1 https://doi.org/10.1016/S0002-9378(00)70504-7	journal	January 2000
Echocardiograhic and anatomic studies of the maternotrophoblastic border during the first trimester of pregnancy Hustin, Jean; Schaaps, Jean-Pierre American Journal of Obstetrics and Gynecology, Vol. 157, Issue 1 https://doi.org/10.1016/S0002-9378(87)80371-X	journal	July 1987
The Physical Properties and Chemical Composition of Human Amniotic Fluid Uyeno, Doko Journal of Biological Chemistry, Vol. 37, Issue 1 https://doi.org/10.1016/S0021-9258(18)86367-0	journal	January 1919
Evaluation of the potential impact of pharmacokinetic differences on tissue dosimetry in offspring during pregnancy and lactation Gentry, P. Robinan; Covington, Tammie R.; Clewell, Harvey J. Regulatory Toxicology and Pharmacology, Vol. 38, Issue 1 https://doi.org/10.1016/S0273-2300(03)00047-3	journal	August 2003
The exposure data landscape for manufactured chemicals Egeghy, Peter P.; Judson, Richard; Gangwal, Sumit Science of The Total Environment, Vol. 414 https://doi.org/10.1016/j.scitotenv.2011.10.046	journal	January 2012
Toxicokinetic models and related tools in environmental risk assessment of chemicals Grech, Audrey; Brochot, Céline; Dorne, Jean-Lou Science of The Total Environment, Vol. 578 https://doi.org/10.1016/j.scitotenv.2016.10.146	journal	February 2017
Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches Coecke, Sandra; Pelkonen, Olavi; Leite, Sofia Batista Toxicology in Vitro, Vol. 27, Issue 5 https://doi.org/10.1016/j.tiv.2012.06.012	journal	August 2013
Reprint of PopGen: A virtual human population generator McNally, Kevin; Cotton, Richard; Hogg, Alex Toxicology, Vol. 332 https://doi.org/10.1016/j.tox.2015.04.014	journal	June 2015
Body composition changes in pregnancy: measurement, predictors and outcomes Widen, E. M.; Gallagher, D. European Journal of Clinical Nutrition, Vol. 68, Issue 6 https://doi.org/10.1038/ejcn.2014.40	journal	March 2014
Physiologically based pharmacokinetics (PBPK) Espié, Pascal; Tytgat, Dominique; Sargentini-Maier, Maria-Laura Drug Metabolism Reviews, Vol. 41, Issue 3 https://doi.org/10.1080/10837450902891360	journal	July 2009
Computational Pharmacokinetics During Developmental Windows of Susceptibility Barton, Hugh A. Journal of Toxicology and Environmental Health, Part A, Vol. 68, Issue 11-12 https://doi.org/10.1080/15287390590912180	journal	June 2005
Perchlorate and Radioiodide Kinetics Across Life Stages in the Human: Using PBPK Models to Predict Dosimetry and Thyroid Inhibition and Sensitive Subpopulations Based on Developmental Stage Clewell, Rebecca A.; Merrill, Elaine A.; Gearhart, Jeffery M. Journal of Toxicology and Environmental Health, Part A, Vol. 70, Issue 5 https://doi.org/10.1080/15287390600755216	journal	February 2007
Evaluation of Physiologically Based Models of Pregnancy and Lactation for Their Application in Children's Health Risk Assessments Corley, Richard A.; Mast, Terryl J.; Carney, Edward W. Critical Reviews in Toxicology, Vol. 33, Issue 2 https://doi.org/10.1080/713611035	journal	January 2003
Characterizing Uncertainty and Variability in Physiologically Based Pharmacokinetic Models: State of the Science and Needs for Research and Implementation Barton, Hugh A.; Chiu, Weihsueh A.; Woodrow Setzer, R. Toxicological Sciences, Vol. 99, Issue 2 https://doi.org/10.1093/toxsci/kfm100	journal	May 2007
FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices Rowlands, J. Craig; Sander, Miriam; Bus, James S. Toxicological Sciences, Vol. 137, Issue 2 https://doi.org/10.1093/toxsci/kft252	journal	November 2013
Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards El-Masri, Hisham; Kleinstreuer, Nicole; Hines, Ronald N. Toxicological Sciences, Vol. 152, Issue 1 https://doi.org/10.1093/toxsci/kfw082	journal	May 2016
Framework for Evaluation of Physiologically‐Based Pharmacokinetic Models for Use in Safety or Risk Assessment Clark, Leona H.; Woodrow Setzer, R.; Barton, Hugh A. Risk Analysis, Vol. 24, Issue 6 https://doi.org/10.1111/j.0272-4332.2004.00561.x	journal	December 2004
A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4: PBPK for pregnancy with time-varying physiological parameters Gaohua, Lu; Abduljalil, Khaled; Jamei, Masoud British Journal of Clinical Pharmacology, Vol. 74, Issue 5 https://doi.org/10.1111/j.1365-2125.2012.04363.x	journal	October 2012
Increase in Plasma Volume During Normal Pregnancy Hytten, F. E.; Paintin, D. B. BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 70, Issue 3 https://doi.org/10.1111/j.1471-0528.1963.tb04922.x	journal	June 1963
A Serial Study in Pregnancy of the Plasma Concentrations of Renin, Corticosteroids, Electrolytes and Proteins and of Haematocrit and Plasma Volume Weir, R. J.; Paintin, D. B.; Brown, J. J. BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 78, Issue 7 https://doi.org/10.1111/j.1471-0528.1971.tb00321.x	journal	July 1971
Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses Zhang, Zufei; Imperial, Marjorie Z.; Patilea-Vrana, Gabriela I. Drug Metabolism and Disposition, Vol. 45, Issue 8 https://doi.org/10.1124/dmd.117.075192	journal	June 2017
Cardiac Output and Central Distribution of Blood Flow in the Human Fetus Mielke, Gunther; Benda, Norbert Circulation, Vol. 103, Issue 12 https://doi.org/10.1161/01.CIR.103.12.1662	journal	March 2001
Studies on the Circulation of the Previable Human Fetus Rudolph, Abraham M.; Heymann, Michael A.; Teramo, Kari A. W. Pediatric Research, Vol. 5, Issue 9 https://doi.org/10.1203/00006450-197109000-00003	journal	September 1971
The Toxicity Data Landscape for Environmental Chemicals Judson, Richard; Richard, Ann; Dix, David J. Environmental Health Perspectives, Vol. 117, Issue 5 https://doi.org/10.1289/ehp.0800168	journal	May 2009
Metodologia para estudo do volume e densidade absoluta da placenta humana de termo Del Nero, Ulisses; Rudge, Marilza Vieira Cunha; Novo, Neil Ferreira Revista Brasileira de Ginecologia e Obstetrícia, Vol. 24, Issue 10 https://doi.org/10.1590/S0100-72032002001000006	journal	December 2002
Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans Anderson, Brian J.; Holford, Nick H. G. Drug Metabolism and Pharmacokinetics, Vol. 24, Issue 1 https://doi.org/10.2133/dmpk.24.25	journal	January 2009
Anatomical, Physiological and Metabolic Changes with Gestational Age during Normal Pregnancy: A Database for Parameters Required in Physiologically Based Pharmacokinetic Modelling Abduljalil, Khaled; Furness, Penny; Johnson, Trevor N. Clinical Pharmacokinetics, Vol. 51, Issue 6 https://doi.org/10.2165/11597440-000000000-00000	journal	January 2012
Recherches mathématiques sur la loi d’accroissement de la population Verhulst, Pierre-François Nouveaux mémoires de l'Académie royale des sciences et belles-lettres de Bruxelles, Vol. 18, Issue 1 https://doi.org/10.3406/marb.1845.3438	journal	January 1845

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59 BASIC BIOLOGICAL SCIENCES
adipose tissue
blood flow
flow rate
hematocrit
kidneys
plasma volume
pregnancy
statistical models

Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation

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References (36)

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