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Title: Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates

Abstract

We present one-dimensional (1-D) lipid bilayer structures that integrate carbon nanotubes with a key biological environment-phospholipid membrane. Our structures consist of lipid bilayers wrapped around carbon nanotubes modified with a hydrophilic polymer cushion layer. Despite high bilayer curvature, the lipid membrane maintains its fluidity and can sustain repeated damage-recovery cycles. We also present the first evidence of spontaneous insertion of pore-forming proteins into 1-D lipid bilayers. These structures could lead to the development of new classes of biosensors and bioelectronic devices.

Authors:
; ; ; ; ;
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
15020090
Report Number(s):
UCRL-JRNL-205932
Journal ID: ISSN 0002-7863; JACSAT; TRN: US200519%%174
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of the American Chemical Society; Journal Volume: 127; Journal Issue: 20
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; CARBON; FUNCTIONALS; LIPIDS; MEMBRANES; NANOTUBES; POLYMERS; PROTEINS

Citation Formats

Artyukhin, A, Shestakov, A, Harper, J, Bakajin, O, Stroeve, P, and Noy, A. Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates. United States: N. p., 2004. Web.
Artyukhin, A, Shestakov, A, Harper, J, Bakajin, O, Stroeve, P, & Noy, A. Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates. United States.
Artyukhin, A, Shestakov, A, Harper, J, Bakajin, O, Stroeve, P, and Noy, A. 2004. "Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates". United States. doi:. https://www.osti.gov/servlets/purl/15020090.
@article{osti_15020090,
title = {Functional One-Dimensional Lipid Bilayers on Carbon Nanotube Templates},
author = {Artyukhin, A and Shestakov, A and Harper, J and Bakajin, O and Stroeve, P and Noy, A},
abstractNote = {We present one-dimensional (1-D) lipid bilayer structures that integrate carbon nanotubes with a key biological environment-phospholipid membrane. Our structures consist of lipid bilayers wrapped around carbon nanotubes modified with a hydrophilic polymer cushion layer. Despite high bilayer curvature, the lipid membrane maintains its fluidity and can sustain repeated damage-recovery cycles. We also present the first evidence of spontaneous insertion of pore-forming proteins into 1-D lipid bilayers. These structures could lead to the development of new classes of biosensors and bioelectronic devices.},
doi = {},
journal = {Journal of the American Chemical Society},
number = 20,
volume = 127,
place = {United States},
year = 2004,
month = 7
}
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