A Comprehensive Approach for Accurate Measurement of Proton-Proton Coupling Constants in the Sugar Ring of DNA
Journal Article
·
· Journal of Magnetic Resonance
Stereo-selective deuteration has been explored in the 12 base pair DNA Dickerson sequence [d(CGCGAATTCGCG)2] as an approach for improving the accuracy of NMR derived, three-bond vicinal proton-proton coupling constants. The coupling constants are useful for DNA structure determination in restrained molecular dynamics calculations.
- Research Organization:
- Pacific Northwest National Lab., Richland, WA (US), Environmental Molecular Sciences Laboratory (US)
- Sponsoring Organization:
- US Department of Energy (US)
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 15011348
- Report Number(s):
- PNNL-SA-32710; JMARF3; 1698; 1852; KP1402010; TRN: US200506%%275
- Journal Information:
- Journal of Magnetic Resonance, Vol. 146, Issue 2; Other Information: PBD: 1 Oct 2000; ISSN 1090-7807
- Country of Publication:
- United States
- Language:
- English
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