Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6
[1]
- Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States
- Stanley Center for Psychiatric Research, Broad Institute of the Massachusetts Institute of Technology and Harvard University, 75 Ames Street, Cambridge, Massachusetts 02142, United States
- Research Organization:
- Brookhaven National Lab. (BNL), Upton, NY (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Basic Energy Sciences (BES)
- DOE Contract Number:
- SC0012704
- OSTI ID:
- 1499558
- Report Number(s):
- BNL-209562-2018-JACI
- Journal Information:
- Biochemistry, Vol. 57, Issue 26; ISSN 0006-2960
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- English
Similar Records
Binding of inhibitors to active-site mutants of CD1, the enigmatic catalytic domain of histone deacetylase 6
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors
Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor
Journal Article
·
Sat Jan 01 00:00:00 EST 2022
· Acta Crystallographica Section F Structural Biology Communications
·
OSTI ID:1499558
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors
Journal Article
·
Sat Jan 01 00:00:00 EST 2022
· Journal of Medicinal Chemistry
·
OSTI ID:1499558
+13 more
Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor
Journal Article
·
Wed Nov 21 00:00:00 EST 2018
· ACS Medicinal Chemistry Letters
·
OSTI ID:1499558
+2 more