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Heterologous pathway to produce terpenes

Patent ·
OSTI ID:1493489

Cells comprising a heterologous metabolic pathway are configured to produce a terpene product containing non-multiples of five carbon, particularly wherein the pathway comprises heterologous Lepidoptera insect juvenile hormone biosynthetic pathway enzymes of the insect's mevalonate pathway.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
10,167,488
Application Number:
15/803,735
OSTI ID:
1493489
Country of Publication:
United States
Language:
English

References (6)

Chemoenzymatic preparation of germacrene analogues journal January 2012
Conversion of a β-Ketoacyl Synthase to a Malonyl Decarboxylase by Replacement of the Active-Site Cysteine with Glutamine journal September 1999
Melamine Deaminase and Atrazine Chlorohydrolase: 98 Percent Identical but Functionally Different journal April 2001
The sequence–structure relationship and protein function prediction journal June 2009
Control of juvenile hormone biosynthesis in Bombyx mori: Cloning of the enzymes in the mevalonate pathway and assessment of their developmental expression in the corpora allata journal August 2007
Purification, properties and heteromeric association of type-1 and type-2 lepidopteran farnesyl diphosphate synthases journal August 2007

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