Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
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journal
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January 2009 |
Structure and function of an irreversible agonist-β2 adrenoceptor complex
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January 2011 |
Structure-Function of the G Protein–Coupled Receptor Superfamily
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January 2013 |
How Ligands Illuminate GPCR Molecular Pharmacology
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July 2017 |
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
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March 2012 |
Structure of the human κ-opioid receptor in complex with JDTic
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March 2012 |
A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor
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March 2010 |
High-resolution crystal structure of the human CB1 cannabinoid receptor
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November 2016 |
Design of MC1R Selective γ-MSH Analogues with Canonical Amino Acids Leads to Potency and Pigmentation
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November 2017 |
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
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September 2011 |
Allosteric regulation of G protein–coupled receptor activity by phospholipids
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November 2015 |
Structure of the chemokine receptor CXCR1 in phospholipid bilayers
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October 2012 |
What Do Structures Tell Us About Chemokine Receptor Function and Antagonism?
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May 2017 |
Multiple ligand-specific conformations of the β2-adrenergic receptor
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August 2011 |
Structure-based drug screening for G-protein-coupled receptors
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May 2012 |
Allosteric coupling from G protein to the agonist-binding pocket in GPCRs
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June 2016 |
A comprehensive map of molecular drug targets
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December 2016 |
Trends in GPCR drug discovery: new agents, targets and indications
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October 2017 |
Crystal structure of opsin in its G-protein-interacting conformation
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September 2008 |
Crystal structure of metarhodopsin II
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March 2011 |
The structural basis of agonist-induced activation in constitutively active rhodopsin
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March 2011 |
Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
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December 2011 |
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
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July 2015 |
Conformational activation of visual rhodopsin in native disc membranes
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March 2015 |
Structural waters define a functional channel mediating activation of the GPCR, rhodopsin
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August 2009 |
Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation
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September 2016 |
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit
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May 2011 |
Retinal Ligand Mobility Explains Internal Hydration and Reconciles Active Rhodopsin Structures
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January 2014 |
Quasi-elastic Neutron Scattering Reveals Ligand-Induced Protein Dynamics of a G-Protein-Coupled Receptor
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October 2016 |
Powdered G-Protein-Coupled Receptors
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journal
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October 2016 |
Bulk-solvent and hydration-shell fluctuations, similar to - and -fluctuations in glasses, control protein motions and functions
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September 2004 |
A unified model of protein dynamics
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February 2009 |
The Retinal Conformation and its Environment in Rhodopsin in Light of a New 2.2Å Crystal Structure
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September 2004 |
Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation
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January 2011 |
Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin
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April 2011 |
A Usual G-Protein-Coupled Receptor in Unusual Membranes
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December 2015 |
Conical intersection dynamics of the primary photoisomerization event in vision
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September 2010 |
Structural study of rhodopsin in detergent micelles by small-angle neutron scattering
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August 1978 |
The suite of small-angle neutron scattering instruments at Oak Ridge National Laboratory
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February 2018 |
Size and Shape of Detergent Micelles Determined by Small-Angle X-ray Scattering
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November 2007 |
Designing Mixed Detergent Micelles for Uniform Neutron Contrast
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October 2017 |
Dependence of Micelle Size and Shape on Detergent Alkyl Chain Length and Head Group
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May 2013 |
Solution Structure of an Intramembrane Aspartyl Protease via Small Angle Neutron Scattering
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February 2018 |
Monomeric G-Protein-Coupled Receptor as a Functional Unit
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June 2005 |
Monomeric G protein-coupled receptor rhodopsin in solution activates its G protein transducin at the diffusion limit
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June 2007 |
Hydration Mediated G-Protein-Coupled Receptor Activation
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journal
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February 2016 |
Functional Characterization of Rhodopsin Monomers and Dimers in Detergents
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journal
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October 2004 |
Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes
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journal
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March 2003 |
Functional and Structural Characterization of Rhodopsin Oligomers
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February 2006 |
Mosaic Energy Landscapes of Liquids and the Control of Protein Conformational Dynamics by Glass-Forming Solvents
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April 2005 |
Termination of Biological Function at Low Temperatures: Glass or Structural Transition?
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April 2018 |
Revisiting volume changes in pressure-induced protein unfolding
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March 2002 |
The Behavior of the Hydrophobic Effect under Pressure and Protein Denaturation
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April 2010 |
Protein folding is slaved to solvent motions
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October 2006 |
Packing at the protein-water interface.
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September 1996 |
Protein hydration in solution: Experimental observation by x-ray and neutron scattering
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March 1998 |
Is the first hydration shell of lysozyme of higher density than bulk water?
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April 2002 |
Complex Dynamics of Water in Protein Confinement
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October 2017 |
Protein hydration dynamics in solution: a critical survey
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August 2004 |
Effects of pressure on the dynamics of an oligomeric protein from deep-sea hyperthermophile
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October 2015 |
Pressure denaturation of metmyoglobin
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October 1973 |
Effects of amino acid substitutions on the pressure denaturation of staphylococcal nuclease as monitored by fluorescence and nuclear magnetic resonance spectroscopy
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May 1993 |
The pressure dependence of hydrophobic interactions is consistent with the observed pressure denaturation of proteins
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February 1998 |
The experimental survey of protein-folding energy landscapes
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August 2005 |
Protein Structure and Hydration Probed by SANS and Osmotic Stress
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April 2008 |
The Protein Folding Problem
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June 2008 |
Structure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressure
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April 2015 |
Probing Conformational Fluctuation of Proteins by Pressure Perturbation
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May 2006 |
On volume changes accompanying conformational transitions of biopolymers
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November 1996 |
Cavities determine the pressure unfolding of proteins
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April 2012 |
A wave-mechanical model of incoherent quasielastic scattering in complex systems
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journal
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August 2014 |
Effects of detergents and high pressures upon the metarhodopsin I.dbr.metarhodopsin II equilibrium
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February 1974 |
Retinal Flip in Rhodopsin Activation?
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June 2015 |