Electrochemical Roughening of Thin-Film Platinum for Neural Probe Arrays and Biosensing Applications

Ivanovskaya, Anna N.; Belle, Anna M.; Yorita, Allison M.; Qian, Fang; Chen, Supin; Tooker, Angela; Lozada, Rose García; Dahlquist, Dylan; Tolosa, Vanessa

doi:10.1149/2.0171812jes

Title: Electrochemical Roughening of Thin-Film Platinum for Neural Probe Arrays and Biosensing Applications

Journal Article · Fri Aug 10 00:00:00 EDT 2018 · Journal of the Electrochemical Society

DOI:https://doi.org/10.1149/2.0171812jes· OSTI ID:1464289

Ivanovskaya, Anna N.;

;

; Qian, Fang; Chen, Supin; Tooker, Angela; Lozada, Rose García; Dahlquist, Dylan; Tolosa, Vanessa

In this work, we report a method for electrochemical roughening of thin-film platinum (Pt) electrodes that increases active surface area, decreases electrode impedance, increases charge injection capacity, increases sensitivity of biosensors and improves adhesion of electrochemically deposited films. First, a well-established technique for electrochemical roughening of thick Pt electrodes (wires and foils) by oxidation-reduction pulses was modified for use on thin-film Pt. Optimal roughening of thin-film Pt electrodes with this established protocol in a sulfuric acid solution was found to occur at about four times lower frequency than that typically used for thick Pt. This modification in established procedure created a 21x surface area increase but showed nanoscale cracks from inter-grain Pt dissolution that compromised film integrity. A crack free surface with Pt nanocrystal re-deposition (20–30 nm in size) and higher enhancement in surface area (44x) was obtained when the electrolyte was switched to a non-adsorbing perchloric acid solution. These electrochemically roughened electrodes have charge injection limits comparable to titanium nitride and just below carbon nanotube-based materials. Roughened microelectrodes showed a 2.8x increase in sensitivity to hydrogen peroxide detection, indicative of improved enzymatic biosensor performance. Platinum iridium and iridium oxide coatings on these roughened surfaces showed an improvement in adhesion.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA); USDOE Laboratory Directed Research and Development (LDRD) Program

Grant/Contract Number:: AC52-07NA27344; 16-ERD-035

OSTI ID:: 1464289

Alternate ID(s):: OSTI ID: 1467810

Report Number(s):: LLNL-JRNL-746398; /jes/165/12/G3125.atom

Journal Information:: Journal of the Electrochemical Society, Journal Name: Journal of the Electrochemical Society Vol. 165 Journal Issue: 12; ISSN 0013-4651

Publisher:: The Electrochemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 17 works

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References (33)

Neural Stimulation with a Carbon Nanotube Microelectrode Array Wang, Ke; Fishman, Harvey A.; Dai, Hongjie Nano Letters, Vol. 6, Issue 9 https://doi.org/10.1021/nl061241t	journal	September 2006
Pseudo-Single-Crystal Electrochemistry on Polycrystalline Electrodes: Visualizing Activity at Grains and Grain Boundaries on Platinum for the Fe ²⁺ /Fe ³⁺ Redox Reaction Aaronson, Barak D. B.; Chen, Chang-Hui; Li, Hongjiao Journal of the American Chemical Society, Vol. 135, Issue 10 https://doi.org/10.1021/ja310632k	journal	February 2013
Silicon Wafer-Based Platinum Microelectrode Array Biosensor for Near Real-Time Measurement of Glutamate in Vivo Wassum, Kate; Tolosa, Vanessa; Wang, Jianjun Sensors, Vol. 8, Issue 8 https://doi.org/10.3390/s8085023	journal	August 2008
Long-Term Stable Adhesion for Conducting Polymers in Biomedical Applications: IrOx and Nanostructured Platinum Solve the Chronic Challenge Boehler, Christian; Oberueber, Felix; Schlabach, Sabine ACS Applied Materials & Interfaces, Vol. 9, Issue 1 https://doi.org/10.1021/acsami.6b13468	journal	December 2016
Investigation of surface-enhanced Raman scattering from platinum electrodes using a confocal Raman microscope: dependence of surface roughening pretreatment Cai, W. B.; Ren, B.; Li, X. Q. Surface Science, Vol. 406, Issue 1-3 https://doi.org/10.1016/S0039-6028(97)01030-3	journal	May 1998
Electrochemically Roughened Palladium Electrodes for Surface-Enhanced Raman Spectroscopy: Methodology, Mechanism, and Application Liu, Zheng; Yang, Zhi-Lin; Cui, Li The Journal of Physical Chemistry C, Vol. 111, Issue 4 https://doi.org/10.1021/jp066122g	journal	February 2007
Neural recording and modulation technologies Chen, Ritchie; Canales, Andres; Anikeeva, Polina Nature Reviews Materials, Vol. 2, Issue 2 https://doi.org/10.1038/natrevmats.2016.93	journal	January 2017
Advanced Neurotechnologies for Chronic Neural Interfaces: New Horizons and Clinical Opportunities Kipke, D. R.; Shain, W.; Buzsaki, G. Journal of Neuroscience, Vol. 28, Issue 46 https://doi.org/10.1523/JNEUROSCI.3879-08.2008	journal	November 2008
Neural Stimulation and Recording Electrodes Cogan, Stuart F. Annual Review of Biomedical Engineering, Vol. 10, Issue 1, p. 275-309 https://doi.org/10.1146/annurev.bioeng.10.061807.160518	journal	August 2008
Raman spectra of pyridine adsorbed at a silver electrode Fleischmann, M.; Hendra, P. J.; McQuillan, A. J. Chemical Physics Letters, Vol. 26, Issue 2, p. 163-166 https://doi.org/10.1016/0009-2614(74)85388-1	journal	May 1974
Ferrocene-mediated enzyme electrode for amperometric determination of glucose Cass, Anthony E. G.; Davis, Graham.; Francis, Graeme D. Analytical Chemistry, Vol. 56, Issue 4 https://doi.org/10.1021/ac00268a018	journal	April 1984
Determination of the Real Surface Area of Pt Electrodes by Hydrogen Adsorption Using Cyclic Voltammetry Doña Rodríguez, José M.; Herrera Melián, José Alberto; Pérez Peña, Jesús Journal of Chemical Education, Vol. 77, Issue 9 https://doi.org/10.1021/ed077p1195	journal	September 2000
Substrate dependent stability of conducting polymer coatings on medical electrodes Green, Rylie A.; Hassarati, Rachelle T.; Bouchinet, Lucie Biomaterials, Vol. 33, Issue 25 https://doi.org/10.1016/j.biomaterials.2012.05.017	journal	September 2012
Electrical Stimulation with Pt Electrodes: II-Estimation of Maximum Surface Redox (Theoretical Non-Gassing) Limits Brummer, S. B.; Turner, M. J. IEEE Transactions on Biomedical Engineering, Vol. BME-24, Issue 5 https://doi.org/10.1109/TBME.1977.326179	journal	September 1977
Chronic electrical stimulation of the auditory nerve using high surface area (HiQ) platinum electrodes Tykocinski, Michael; Duan, Yvonne; Tabor, Bruce Hearing Research, Vol. 159, Issue 1-2 https://doi.org/10.1016/S0378-5955(01)00320-3	journal	September 2001
A Review of Organic and Inorganic Biomaterials for Neural Interfaces Fattahi, Pouria; Yang, Guang; Kim, Gloria Advanced Materials, Vol. 26, Issue 12 https://doi.org/10.1002/adma.201304496	journal	February 2014
Polymers for neural implants Hassler, Christina; Boretius, Tim; Stieglitz, Thomas Journal of Polymer Science Part B: Polymer Physics, Vol. 49, Issue 1, p. 18-33 https://doi.org/10.1002/polb.22169	journal	November 2010
Fuzzy gold electrodes for lowering impedance and improving adhesion with electrodeposited conducting polymer films Cui, Xinyan; Martin, David C. Sensors and Actuators A: Physical, Vol. 103, Issue 3 https://doi.org/10.1016/S0924-4247(02)00427-2	journal	February 2003
The real condition of oxidized pt electrodes Tilak, B. V.; Conway, B. E.; Angerstein-Kozlowska, H. Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, Vol. 48, Issue 1 https://doi.org/10.1016/S0022-0728(73)80290-6	journal	November 1973
Chronic neural recordings using silicon microelectrode arrays electrochemically deposited with a poly(3,4-ethylenedioxythiophene) (PEDOT) film Ludwig, Kip A.; Uram, Jeffrey D.; Yang, Junyan Journal of Neural Engineering, Vol. 3, Issue 1 https://doi.org/10.1088/1741-2560/3/1/007	journal	March 2006
Anodically Electrodeposited Iridium Oxide Films (AEIROF) from Alkaline Solutions for Electrochromic Display Devices Yamanaka, Kazusuke Japanese Journal of Applied Physics, Vol. 28, Issue Part 1, No. 4 https://doi.org/10.1143/JJAP.28.632	journal	April 1989
Electrodeposited iridium oxide for neural stimulation and recording electrodes Meyer, R. D.; Cogan, S. F.; Nguyen, T. H. IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol. 9, Issue 1 https://doi.org/10.1109/7333.918271	journal	March 2001
Electrical stimulation with Pt electrodes. VIII. Electrochemically safe charge injection limits with 0.2 ms pulses (neuronal application) Rose, T. L.; Robblee, L. S. IEEE Transactions on Biomedical Engineering, Vol. 37, Issue 11 https://doi.org/10.1109/10.61038	journal	January 1990
In vitro electrical properties for iridium oxide versus titanium nitride stimulating electrodes Weiland, J. D.; Anderson, D. J.; Humayun, M. S. IEEE Transactions on Biomedical Engineering, Vol. 49, Issue 12 https://doi.org/10.1109/TBME.2002.805487	journal	December 2002
Laser patterning of platinum electrodes for safe neurostimulation Green, R. A.; Matteucci, P. B.; Dodds, C. W. D. Journal of Neural Engineering, Vol. 11, Issue 5 https://doi.org/10.1088/1741-2560/11/5/056017	journal	September 2014
Effects of electrolytes used in roughening gold substrates by oxidation–reduction cycles on surface-enhanced Raman scattering Liu, Yu-Chuan; Wang, Chee-Chan; Tsai, Chun-En Electrochemistry Communications, Vol. 7, Issue 12 https://doi.org/10.1016/j.elecom.2005.09.030	journal	December 2005
Thin film platinum cuff electrodes for neurostimulation: in vitro approach of safe neurostimulation parameters Mailley, Sophie; Hyland, Marc; Mailley, Pascal Bioelectrochemistry, Vol. 63, Issue 1-2 https://doi.org/10.1016/j.bioelechem.2003.10.033	journal	June 2004
Investigating the Interfacial Properties of Electrochemically Roughened Platinum Electrodes for Neural Stimulation Weremfo, Alexander; Carter, Paul; Hibbert, D. Brynn Langmuir, Vol. 31, Issue 8 https://doi.org/10.1021/la504876n	journal	February 2015
Electrode modifications to lower electrode impedance and improve neural signal recording sensitivity Chung, T.; Wang, J. Q.; Wang, J. Journal of Neural Engineering, Vol. 12, Issue 5 https://doi.org/10.1088/1741-2560/12/5/056018	journal	September 2015
Electrodeposition and Characterization of Thin-Film Platinum-Iridium Alloys for Biological Interfaces Petrossians, Artin; Whalen III, John J.; Weiland, James D. Journal of The Electrochemical Society, Vol. 158, Issue 5 https://doi.org/10.1149/1.3559477	journal	January 2011
Microfabricated, amperometric, enzyme-based biosensors for in vivo applications Weltin, Andreas; Kieninger, Jochen; Urban, Gerald A. Analytical and Bioanalytical Chemistry, Vol. 408, Issue 17 https://doi.org/10.1007/s00216-016-9420-4	journal	March 2016
Electron transfer processes occurring on platinum neural stimulating electrodes: a tutorial on the i ( V _e ) profile Kumsa, Doe W.; Bhadra, Narendra; Hudak, Eric M. Journal of Neural Engineering, Vol. 13, Issue 5 https://doi.org/10.1088/1741-2560/13/5/052001	journal	August 2016
Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces Lacour, Stéphanie P.; Benmerah, Samia; Tarte, Edward Medical & Biological Engineering & Computing, Vol. 48, Issue 10, p. 945-954 https://doi.org/10.1007/s11517-010-0644-8	journal	June 2010

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