Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans
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December 2015
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
F., Salazar-Gonzalez, Jesus; P., Busch, Michael; S., Perelson, Alan
The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/f6s9-vz03
text
January 2008
HIV-Specific Probabilistic Models of Protein Evolution
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June 2007
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
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October 2011
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
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January 2014
Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide
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January 2017
Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy
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October 2015
Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection
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March 2016
Antibody responses to envelope glycoproteins in HIV-1 infection
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May 2015
Analysis of a Clonal Lineage of HIV-1 Envelope V2/V3 Conformational Epitope-Specific Broadly Neutralizing Antibodies and Their Inferred Unmutated Common Ancestors
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July 2011
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody
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April 2016
Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants
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October 2015
Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
text
January 2008
Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140
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May 2015
Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape
Tandile, Hermanus,; Abdool, Karim, Quarraisha; E., Lambson, Bronwen
The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/e8bk-6082
text
January 2012
Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
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June 2014
Two Classes of Broadly Neutralizing Antibodies within a Single Lineage Directed to the High-Mannose Patch of HIV Envelope
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November 2014
Two Distinct Broadly Neutralizing Antibody Specificities of Different Clonal Lineages in a Single HIV-1-Infected Donor: Implications for Vaccine Design
journal
February 2012
Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies
text
January 2010
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
journal
May 2008
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
S., Perelson, Alan; Christina, Ochsenbauer-Jambor,; C., Kappas, John
The University of North Carolina at Chapel Hill University Libraries
https://doi.org/10.17615/1n1a-3d64
text
January 2009
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
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April 2013
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
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January 2013
Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
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August 2013
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes
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November 2015
Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
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July 2015
Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Individual
text
January 2011
Genetic Signatures in the Envelope Glycoproteins of HIV-1 that Associate with Broadly Neutralizing Antibodies
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October 2010
Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies
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September 2014
Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Individual
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May 2011
Structure and immune recognition of trimeric pre-fusion HIV-1 Env
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October 2014
Biochemical Analysis of Hypermutational Targeting by Wild Type and Mutant Activation-induced Cytidine Deaminase
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September 2004
Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
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July 2014
Reconstructing a B-cell clonal lineage. I. Statistical inference of unobserved ancestors
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January 2013
Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide
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March 2017
B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
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May 2012
Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies
text
January 2014
A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
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September 2013
HIV-1 neutralizing antibodies: understanding nature's pathways
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June 2013
Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Broadens Neutralization of HIV
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May 2014
Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape
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October 2012
Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors
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October 2013
HIV Transmission
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October 2012
Founder Effects in the Assessment of HIV Polymorphisms and HLA Allele Associations
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March 2007
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120
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May 2013
The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
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November 2013
Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
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May 2013
Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data
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January 2013
Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
journal
October 2008
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
journal
June 2009
Tiered Categorization of a Diverse Panel of HIV-1 Env Pseudoviruses for Assessment of Neutralizing Antibodies
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November 2009
The Nucleotide-Replacement Spectrum Under Somatic Hypermutation Exhibits Microsequence Dependence That Is Strand-Symmetric and Distinct from That Under Germline Mutation
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February 2000
Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots.
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March 1993
N332-Directed Broadly Neutralizing Antibodies Use Diverse Modes of HIV-1 Recognition: Inferences from Heavy-Light Chain Complementation of Function
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February 2013
Chemical Synthesis of Highly Congested gp120 V1V2 N -Glycopeptide Antigens for Potential HIV-1-Directed Vaccines
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August 2013
Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia
text
January 2008
High throughput functional analysis of HIV-1 env genes without cloning
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July 2007
Broad neutralization coverage of HIV by multiple highly potent antibodies
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September 2011
Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
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September 2009
Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
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October 2012
Complete epitopes for vaccine design derived from a crystal structure of the broadly neutralizing antibodies PGT128 and 8ANC195 in complex with an HIV-1 Env trimer
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September 2015
Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies
journal
December 2013
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
text
January 2009