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System and method for dose verification and gamma ray imaging in ion beam therapy

Patent ·
OSTI ID:1415032
This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.
Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
9,849,307
Application Number:
14/886,862
OSTI ID:
1415032
Country of Publication:
United States
Language:
English

References (11)

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conference August 2009
In-beam PET measurements of β+ radioactivity induced by proton beams journal November 2001
Prompt gamma detection for range verification in proton therapy journal March 2012
Compressive coded aperture superresolution image reconstruction conference March 2008
Coded aperture imaging: a Fourier space analysis journal January 1987
Prompt gamma imaging with a slit camera for real-time range control in proton therapy journal May 2012
Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge-shaped slit journal December 2011
Heavy-ion tumor therapy: Physical and radiobiological benefits journal February 2010
Development of array-type prompt gamma measurement system for in vivo range verification in proton therapy journal March 2012
Optimal coded aperture patterns for improved SNR in nuclear medicine imaging
  • Accorsi, Roberto; Gasparini, Francesca; Lanza, Richard C
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 474, Issue 3, p. 273-284 https://doi.org/10.1016/S0168-9002(01)01326-2
journal December 2001

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46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY