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Title: System and method for dose verification and gamma ray imaging in ion beam therapy

Patent ·
OSTI ID:1415032

This disclosure provides systems, methods, and apparatus related to ion beam therapy. In one aspect, a system includes a position sensitive detector and a collimator. The position sensitive detector configured to detect gamma rays generated by an ion beam interacting with a target. The collimator is positioned between the target and the position sensitive detector. The collimator includes a plurality of knife-edge slits, with a first knife-edge slit intersecting with a second knife-edge slit.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-05CH11231
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Number(s):
9,849,307
Application Number:
14/886,862
OSTI ID:
1415032
Resource Relation:
Patent File Date: 2015 Oct 19
Country of Publication:
United States
Language:
English

References (14)

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Prompt gamma imaging with a slit camera for real-time range control in proton therapy journal May 2012
Coded aperture computed tomography
  • Choi, Kerkil; Brady, David J.; Rogers, Stanley
  • Adaptive Coded Aperture Imaging, Non-Imaging, and Unconventional Imaging Sensor Systems, Vol. 7468 https://doi.org/10.1117/12.825277
conference August 2009
In-beam PET measurements of β+ radioactivity induced by proton beams journal November 2001
Coded aperture imaging: a Fourier space analysis journal January 1987
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Optimal coded aperture patterns for improved SNR in nuclear medicine imaging
  • Accorsi, Roberto; Gasparini, Francesca; Lanza, Richard C
  • Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 474, Issue 3, p. 273-284 https://doi.org/10.1016/S0168-9002(01)01326-2
journal December 2001
Prompt gamma detection for range verification in proton therapy journal March 2012
Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife-edge-shaped slit journal December 2011

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46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY