The Effects of a Series of ω-Phosphonic α-Carboxylic Amino Acids on Electrically Evoked and Excitant Amino Acid-Induced Responses in Isolated Spinal cord Preparations
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January 1982 |
Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors
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March 2014 |
Substituted Pyrazoles as Hepatoselective HMG-CoA Reductase Inhibitors: Discovery of (3 R ,5 R )-7-[2-(4-Fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2 H -pyrazol-3-yl]-3,5-dihydroxyheptanoic Acid (PF-3052334) as a Candidate for the Treatment of Hypercholesterolemia
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January 2008 |
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
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March 1994 |
The selectivity of conantokin-G for ion channel inhibition of NR2B subunit-containing NMDA receptors is regulated by amino acid residues in the S2 region of NR2B
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August 2009 |
Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
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March 1994 |
N -Methyl-d-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse
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August 2009 |
NMDA receptor modulators: an updated patent review (2013 – 2014)
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October 2014 |
A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABA A receptors
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June 2014 |
Some Quantitative uses of drug Antagonists
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March 1959 |
Equilibrium Constants for ( R )-[( S )-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N -Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission
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June 2006 |
Novel Mode of Antagonist Binding in NMDA Receptors Revealed by the Crystal Structure of the GluN1-GluN2A Ligand-Binding Domain Complexed to NVP-AAM077
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May 2017 |
Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine
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March 1991 |
Spatial Localization of the K+ Channel Selectivity Filter by Mutant Cycle–Based Structure Analysis
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January 1996 |
Structural and Mechanistic Determinants of a Novel Site for Noncompetitive Inhibition of GluN2D-Containing NMDA Receptors
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March 2011 |
Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties
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April 2017 |
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
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August 2010 |
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
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June 2003 |
Improved Fourier coefficients for maps using phases from partial structures with errors
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May 1986 |
Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator
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September 2014 |
Optimized N-phenyl-N′-(2-chloroethyl)ureas as potential antineoplastic agents: Synthesis and growth inhibition activity
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December 2005 |
Structural Insights into Competitive Antagonism in NMDA Receptors
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January 2014 |
Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N -Methyl- d -aspartate Receptor as Potential Imaging Agents for Brain
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December 2016 |
A Medicinal Chemist’s Guide to Molecular Interactions
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July 2010 |
Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors
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July 2005 |
Crystal structure of a heterotetrameric NMDA receptor ion channel
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May 2014 |
A Novel Family of Negative and Positive Allosteric Modulators of NMDA Receptors
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September 2010 |
Molecular pharmacology of human NMDA receptors
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September 2012 |
Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes: Control of glycine potency in NMDARs by NR2 binding domains
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journal
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January 2008 |
Structural Determinants of Agonist Efficacy at the Glutamate Binding Site of N -Methyl-d-Aspartate Receptors
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April 2013 |
5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition
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April 2002 |
The time course of glutamate in the synaptic cleft
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November 1992 |
The Majority of N -Methyl-d-Aspartate Receptor Complexes in Adult Rat Cerebral Cortex Contain at Least Three Different Subunits (NR1/NR2A/NR2B)
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January 1997 |
NMDA receptor structures reveal subunit arrangement and pore architecture
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June 2014 |
The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
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October 1984 |
Concentration-jump experiments with NMDA antagonists in mouse cultured hippocampal neurons
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June 1990 |
MolProbity : all-atom structure validation for macromolecular crystallography
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December 2009 |
Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles: NMDA receptor gating
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February 2005 |
Strategy for analysing the co-operativity of intramolecular interactions in peptides and proteins
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August 1990 |
Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors
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September 2016 |
Features and development of Coot
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March 2010 |
Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators
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September 2012 |
Taking The Time To Study Competitive Antagonism: KB versus IC50 measurements
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March 2007 |
Analysis of competitive agonist-antagonist interactions by nonlinear regression
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October 1995 |
Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
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September 2009 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
Triheteromeric NR1/NR2A/NR2B Receptors Constitute the Major N -Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses
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December 2010 |
MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit
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February 2016 |
New advances in NMDA receptor pharmacology
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December 2011 |
Identification of Subunit- and Antagonist-Specific Amino Acid Residues in the N -Methyl-d-aspartate Receptor Glutamate-Binding Pocket
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March 2005 |
The effect of competitive antagonist chain length on NMDA receptor subunit selectivity
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March 2005 |
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
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May 2013 |
Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function
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March 2016 |
Novel 3-Carboxy- and 3-Phosphonopyrazoline Amino Acids as Potent and Selective NMDA Receptor Antagonists: Design, Synthesis, and Pharmacological Characterization
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July 2010 |
Structure-activity analysis of binding kinetics for NMDA receptor competitive antagonists: the influence of conformational restriction
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September 1991 |
CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
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October 2012 |
Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
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December 1973 |
Phaser crystallographic software
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July 2007 |
Crystal Structure and Pharmacological Characterization of a Novel N -Methyl-d-aspartate (NMDA) Receptor Antagonist at the GluN1 Glycine Binding Site
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September 2013 |
Synthesis of a protected enantiomerically pure 2-deoxystreptamine derivative from d-allylglycine
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April 2004 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |