Multinozzle emitter arrays for ultrahigh-throughput nanoelectrospray mass spectrometry

Wang, Daojing; Mao, Pan; Wang, Hung-Ta; Yang, Peidong

Title: Multinozzle emitter arrays for ultrahigh-throughput nanoelectrospray mass spectrometry

Patent · Tue Oct 17 00:00:00 EDT 2017

OSTI ID:1399781

Wang, Daojing; Mao, Pan; Wang, Hung-Ta; Yang, Peidong

The present invention provides for a structure comprising a plurality of emitters, wherein a first nozzle of a first emitter and a second nozzle of a second emitter emit in two directions that are not or essentially not in the same direction; wherein the walls of the nozzles and the emitters form a monolithic whole. The present invention also provides for a structure comprising an emitter with a sharpened end from which the emitter emits; wherein the emitters forms a monolithic whole. The present invention also provides for a fully integrated separation of proteins and small molecules on a silicon chip before the electrospray mass spectrometry analysis.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of The University of California

Patent Number(s):: 9,793,477

Application Number:: 14/137,840

OSTI ID:: 1399781

Resource Relation:: Patent File Date: 2013 Dec 20

Country of Publication:: United States

Language:: English

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