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Title: Method and apparatus for multispray emitter for mass spectrometry

Abstract

A method and apparatus that utilizes two or more emitters simultaneously to form an electrospray of a sample that is then directed into a mass spectrometer, thereby increasing the total ion current introduced into an electrospray ionization mass spectrometer, given a liquid flow rate of a sample. The method and apparatus are most conveniently constructed as an array of spray emitters fabricated on a single chip, however, the present invention encompasses any apparatus wherein two or more emitters are simultaneously utilized to form an electrospray of a sample that is then directed into a mass spectrometer.

Inventors:
; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175170
Patent Number(s):
6,831,274
Application Number:
10/091,833
Assignee:
Battelle Memorial Institute (Richland, WA)
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING

Citation Formats

Smith, Richard D., Tang, Keqi, and Lin, Yuehe. Method and apparatus for multispray emitter for mass spectrometry. United States: N. p., 2004. Web.
Smith, Richard D., Tang, Keqi, & Lin, Yuehe. Method and apparatus for multispray emitter for mass spectrometry. United States.
Smith, Richard D., Tang, Keqi, and Lin, Yuehe. Tue . "Method and apparatus for multispray emitter for mass spectrometry". United States. https://www.osti.gov/servlets/purl/1175170.
@article{osti_1175170,
title = {Method and apparatus for multispray emitter for mass spectrometry},
author = {Smith, Richard D. and Tang, Keqi and Lin, Yuehe},
abstractNote = {A method and apparatus that utilizes two or more emitters simultaneously to form an electrospray of a sample that is then directed into a mass spectrometer, thereby increasing the total ion current introduced into an electrospray ionization mass spectrometer, given a liquid flow rate of a sample. The method and apparatus are most conveniently constructed as an array of spray emitters fabricated on a single chip, however, the present invention encompasses any apparatus wherein two or more emitters are simultaneously utilized to form an electrospray of a sample that is then directed into a mass spectrometer.},
doi = {},
url = {https://www.osti.gov/biblio/1175170}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {12}
}

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Works referenced in this record:

A Fully Integrated Monolithic Microchip Electrospray Device for Mass Spectrometry
journal, September 2000


Microfluidic Devices Connected to Fused-Silica Capillaries with Minimal Dead Volume
journal, August 1999


The current emitted by highly conducting Taylor cones
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Multichannel Microchip Electrospray Mass Spectrometry
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A Microfabricated Device for Rapid Protein Identification by Microelectrospray Ion Trap Mass Spectrometry
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A Micromachined Chip-Based Electrospray Source for Mass Spectrometry
journal, January 2000


Generation of Multiple Electrosprays Using Microfabricated Emitter Arrays for Improved Mass Spectrometric Sensitivity
journal, April 2001


Microfabricated Devices for Capillary Electrophoresis−Electrospray Mass Spectrometry
journal, August 1999


Generating Electrospray from Microchip Devices Using Electroosmotic Pumping
journal, March 1997