Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Huerta, Carlos; Jiang, Xin; Trevino, Isaac; Bender, Christopher F.; Ferguson, Deborah A.; Probst, Brandon; Swinger, Kerren K.; Stoll, Vincent S.; Thomas, Philip J.; Dulubova, Irina; Visnick, Melean; Wigley, W. Christian

doi:10.1016/j.bbagen.2016.07.026

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding

Journal Article · Tue Nov 01 00:00:00 EDT 2016 · Biochimica et Biophysica Acta - General Subjects

DOI:https://doi.org/10.1016/j.bbagen.2016.07.026· OSTI ID:1396468

Huerta, Carlos; Jiang, Xin; Trevino, Isaac; Bender, Christopher F.; Ferguson, Deborah A.; Probst, Brandon; Swinger, Kerren K.; Stoll, Vincent S.; Thomas, Philip J.; Dulubova, Irina; Visnick, Melean; Wigley, W. Christian

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View Accepted Manuscript (Publisher)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1396468

Alternate ID(s):: OSTI ID: 1347780

Journal Information:: Biochimica et Biophysica Acta - General Subjects, Journal Name: Biochimica et Biophysica Acta - General Subjects Journal Issue: 11 PA Vol. 1860; ISSN 0304-4165

Publisher:: ElsevierCopyright Statement

Country of Publication:: Netherlands

Language:: English

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