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Vibrational sum frequency generation digital holography

Journal Article · · Applied Physics Letters
DOI:https://doi.org/10.1063/1.4986451· OSTI ID:1388913
Here, we demonstrated a molecular spectroscopic imaging method by integrating the capabilities of holography and vibrational sum frequency generation (SFG) spectroscopy. SFG is a second-order nonlinear optical process that can probe molecular vibration resonance. SFG also poses stringent requirement of noncentro-symmetry, useful for suppressing interfering contributions in a complex environment. Further, holographic detection captures a wide-field complex SFG signal including both the amplitude and phase information, thus enabling new opportunities for three-dimensional label free imaging.
Research Organization:
Energy Frontier Research Centers (EFRC) (United States). Center for Lignocellulose Structure and Formation (CLSF)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
Grant/Contract Number:
SC0001090
OSTI ID:
1388913
Journal Information:
Applied Physics Letters, Journal Name: Applied Physics Letters Journal Issue: 25 Vol. 110; ISSN 0003-6951
Publisher:
American Institute of Physics (AIP)Copyright Statement
Country of Publication:
United States
Language:
English

References (19)

Distinction between some saccharides in scattered optical sum frequency intensity images journal December 2005
Wetting effect on optical sum frequency generation (SFG) spectra of d-glucose, d-fructose, and sucrose journal March 2015
Multimodal Broadband Vibrational Sum Frequency Generation (MM-BB-V-SFG) Spectrometer and Microscope journal December 2015
Selective Detection of Crystalline Cellulose in Plant Cell Walls with Sum-Frequency-Generation (SFG) Vibration Spectroscopy journal July 2011
Sum Frequency Generation Microscopy of Microcontact-Printed Mixed Self-Assembled Monolayers journal February 2006
Noninvasive molecular imaging of small living subjects using Raman spectroscopy journal March 2008
Digital recording and numerical reconstruction of holograms journal August 2002
Coherent Anti-Stokes Raman Holography for Chemically Selective Single-Shot Nonscanning 3D Imaging journal March 2010
Three-Dimensional Vibrational Imaging by Coherent Anti-Stokes Raman Scattering journal May 1999
Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy journal December 2008
Coherent Anti-Stokes Raman Scattering Holography: Theory and Experiment journal June 2012
Biomolecular Imaging with Coherent Nonlinear Vibrational Microscopy journal April 2013
Harmonic holography: a new holographic principle journal November 2007
Holographic coherent anti-Stokes Raman scattering bio-imaging journal January 2012
Compressive Holography journal January 2009
Inline holographic coherent anti-Stokes Raman microscopy journal January 2010
Label-free second harmonic generation holographic microscopy of biological specimens journal January 2010
Compressive coherent anti-Stokes Raman scattering holography journal January 2015
Rapid vibrational imaging with sum frequency generation microscopy journal January 2011

Cited By (1)

Probing cellulose structures with vibrational spectroscopy journal January 2019