skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Effect of charge, hydrophobicity, and sequence of nucleoporins on the translocation of model particles through the nuclear pore complex

Journal Article · · Proceedings of the National Academy of Sciences of the United States of America

Research Organization:
Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
DOE Contract Number:
SC0000989
OSTI ID:
1384626
Journal Information:
Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 9; Related Information: CBES partners with Northwestern University (lead); Harvard University; New York University; Pennsylvania State University; University of Michigan; University of Pittsburgh; ISSN 0027-8424
Publisher:
National Academy of Sciences, Washington, DC (United States)
Country of Publication:
United States
Language:
English

References (35)

The Structure of the Nuclear Pore Complex journal July 2011
The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism journal February 2000
Transport-Related Structures and Processes of the Nuclear Pore Complex Studied through Molecular Dynamics journal March 2009
Simulations of nuclear pore transport yield mechanistic insights and quantitative predictions journal June 2011
Amyloid-like interactions within nucleoporin FG hydrogels journal March 2010
Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes journal October 2012
The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion journal June 2002
Translocation through the nuclear pore: Kaps pave the way journal April 2009
Probing a Structural Model of the Nuclear Pore Complex Channel through Molecular Dynamics journal April 2010
Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP 1 1Edited by I. B. Holland journal October 1999
Nucleocytoplasmic Transport: Navigating the Channel: Nucleocytoplasmic Transport journal March 2003
Self-organization of grafted polyelectrolyte layers via the coupling of chemical equilibrium and physical interactions journal March 2010
Natively Unfolded Nucleoporins Gate Protein Diffusion across the Nuclear Pore Complex journal April 2007
Flexible Gates: Dynamic Topologies and Functions for FG Nucleoporins in Nucleocytoplasmic Transport journal December 2009
Translocation Through the Nuclear Pore Complex: Selectivity and Speed by Reduction-of-Dimensionality: Translocation Through the Nuclear Pore journal March 2005
A jumbo problem: mapping the structure and functions of the nuclear pore complex journal February 2012
Determining the architectures of macromolecular assemblies journal November 2007
Ion Transport and Molecular Organization Are Coupled in Polyelectrolyte-Modified Nanopores journal November 2011
The molecular architecture of the nuclear pore complex journal November 2007
Self-regulated viscous channel in the nuclear pore complex journal April 2012
Weak polyelectrolytes tethered to surfaces: Effect of geometry, acid–base equilibrium and electrical permittivity journal January 2006
Brownian Dynamics Simulation of Nucleocytoplasmic Transport: A Coarse-Grained Model for the Functional State of the Nuclear Pore Complex journal June 2011
How and Why Nanoparticle’s Curvature Regulates the Apparent p K a of the Coating Ligands journal February 2011
Nanomechanical Basis of Selective Gating by the Nuclear Pore Complex journal October 2007
Kinetic analysis of translocation through nuclear pore complexes journal March 2001
Welcome to the nucleus: CAN I take your coat? journal December 2001
Metastable Network Model of Protein Transport through Nuclear Pores journal April 2004
The Part and the Whole: functions of nucleoporins in nucleocytoplasmic transport journal August 2010
Selectivity mechanism of the nuclear pore complex characterized by single cargo tracking journal September 2010
Morphology Control of Hairy Nanopores journal May 2011
Structural Basis for the Interaction between FxFG Nucleoporin Repeats and Importin-β in Nuclear Trafficking journal July 2000
Imaging of single-molecule translocation through nuclear pore complexes journal August 2004
Efficiency, Selectivity, and Robustness of Nucleocytoplasmic Transport journal January 2007
Charge as a Selection Criterion for Translocation through the Nuclear Pore Complex journal April 2010
Virtual gating and nuclear transport: the hole picture journal December 2003