Cells and methods for producing fatty alcohols

Pfleger, Brian F.; Youngquist, Tyler J.

Cells and methods for producing fatty alcohols

Patent · Tue Jul 18 04:00:00 EDT 2017

OSTI ID:1371919

Pfleger, Brian F.; Youngquist, Tyler J.

Recombinant cells and methods for improved yield of fatty alcohols. The recombinant cells harbor a recombinant thioesterase gene, a recombinant acyl-CoA synthetase gene, and a recombinant acyl-CoA reductase gene. In addition, a gene product from one or more of an acyl-CoA dehydrogenase gene, an enoyl-CoA hydratase gene, a 3-hydroxyacyl-CoA dehydrogenase gene, and a 3-ketoacyl-CoA thiolase gene in the recombinant cells is functionally deleted. Culturing the recombinant cells produces fatty alcohols at high yields.

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Research Organization:: WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC02-07ER64494

Assignee:: WISCONSIN ALUMNI RESEARCH FOUNDATION

Patent Number(s):: 9,708,630

Application Number:: 14/509,408

OSTI ID:: 1371919

Country of Publication:: United States

Language:: English

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