NMR and enzymology of modified DNA/protein interactions
Conference
·
OSTI ID:134860
- Battelle Pacific Northwest Lab., Richland, WA (United States)
We have found distinct DNA structure and base dynamics precisely at the TpA cleavage site in the TTTAAA AHA III endonuclease restriction sequence. Hence, the unusual base stacking and mobility found in this sequence may be important to the mechanism of enzymatic cleavage of the phophodiester bond.
- Research Organization:
- New York Academy of Sciences, New York, NY (United States)
- DOE Contract Number:
- FG06-89ER75522
- OSTI ID:
- 134860
- Report Number(s):
- CONF-9307221-; TRN: 95:007741-0027
- Resource Relation:
- Conference: DNA damage: effects on DNA structure and protein recognition, Burlington, VT (United States), 31 Jul - 4 Aug 1993; Other Information: PBD: 1994; Related Information: Is Part Of DNA damage: Effects on DNA structure and protein recognition; Wallace, S.S.; Van Houten, B.; Kow, Yoke Wah [eds.]; PB: 395 p.
- Country of Publication:
- United States
- Language:
- English
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