Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors
Journal Article
·
· Journal of Medicinal Chemistry
Abstract not provided
- Research Organization:
- Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
- Sponsoring Organization:
- INDUSTRY
- OSTI ID:
- 1347756
- Journal Information:
- Journal of Medicinal Chemistry, Journal Name: Journal of Medicinal Chemistry Journal Issue: 18 Vol. 59; ISSN 0022-2623
- Publisher:
- American Chemical Society (ACS)
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
Discovery of furo[2,3-d][1,3]thiazinamines as beta amyloid cleaving enzyme-1 (BACE1) inhibitors
]Discovery of AM-6494: A Potent and Orally Efficacious [beta]-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2
Discovery of potent iminoheterocycle BACE1 inhibitors
Journal Article
·
Wed Nov 30 23:00:00 EST 2016
· Bioorganic & Medicinal Chemistry Letters
·
OSTI ID:1347755
]Discovery of AM-6494: A Potent and Orally Efficacious [beta]-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2
Journal Article
·
Thu Apr 02 00:00:00 EDT 2020
· J. Med. Chem.
·
OSTI ID:1608844
Discovery of potent iminoheterocycle BACE1 inhibitors
Journal Article
·
Fri Sep 18 00:00:00 EDT 2015
· Bioorg. Med. Chem. Lett.
·
OSTI ID:1194208