Miniature acoustic wave lysis system and uses thereof

Branch, Darren W.; Vreeland, Erika Cooley; Smith, Gennifer Tanabe

Title: Miniature acoustic wave lysis system and uses thereof

Patent · Tue Dec 06 00:00:00 EST 2016

OSTI ID:1334665

Branch, Darren W.; Vreeland, Erika Cooley; Smith, Gennifer Tanabe

The present invention relates to an acoustic lysis system including a disposable cartridge that can be reversibly coupled to a platform having a small, high-frequency piezoelectric transducer array. In particular, the system releases viable DNA, RNA, and proteins from human or bacterial cells, without chemicals or additional processing, to enable high-speed sample preparation for clinical point-of-care medical diagnostics and use with nano/microfluidic cartridges. Also described herein are methods of making and using the system of the invention.

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Research Organization:: Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC04-94AL85000

Assignee:: Sandia Corporation (Albuquerque, NM)

Patent Number(s):: 9,512,421

Application Number:: 14/318,364

OSTI ID:: 1334665

Resource Relation:: Patent File Date: 2014 Jun 27

Country of Publication:: United States

Language:: English

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