Current understanding of the correlation of lignin structure with biomass recalcitrance

Li, Mi; Pu, Yunqiao; Ragauskas, Arthur J.

doi:10.3389/fchem.2016.00045

Current understanding of the correlation of lignin structure with biomass recalcitrance

Journal Article · Fri Nov 18 04:00:00 EST 2016 · Frontiers in Chemistry

DOI:https://doi.org/10.3389/fchem.2016.00045· OSTI ID:1333663

Li, Mi ^[1]; Pu, Yunqiao ^[1]; Ragauskas, Arthur J. ^[2]

Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States); Univ. of Tennessee Institute of Agriculture, Knoxville, TN (United States)

Lignin, a complex aromatic polymer in terrestrial plants, contributes significantly to biomass recalcitrance to microbial and/or enzymatic deconstruction. To reduce biomass recalcitrance, substantial endeavors have been exerted on pretreatment and lignin engineering in the past few decades. Lignin removal and/or alteration of lignin structure have been shown to result in reduced biomass recalcitrance with improved cell wall digestibility. While high lignin content is usually a barrier to a cost-efficient application of bioresources to biofuels, the direct correlation of lignin structure and its concomitant properties with biomass remains unclear due to the complexity of cell wall and lignin structure. Advancement in application of biorefinery to production of biofuels, chemicals, and bio-derived materials necessitates a fundamental understanding of the relationship of lignin structure and biomass recalcitrance. In this mini-review, we focus on recent investigations on the influence of lignin chemical properties on bioprocessability—pretreatment and enzymatic hydrolysis of biomass. Furthermore, lignin-enzyme interactions and the effects of lignin compositional units, hydroxycinnamates, and lignin functional groups on biomass recalcitrance have been highlighted, which will be useful not only in addressing biomass recalcitrance but also in deploying renewable lignocelluloses efficiently.

View Accepted Manuscript (DOE)

Research Organization:: Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States). BioEnergy Science Center (BESC); Joint Institute for Biological Sciences (JIBS)

Sponsoring Organization:: USDOE Office of Science (SC)

Grant/Contract Number:: AC05-00OR22725

OSTI ID:: 1333663

Journal Information:: Frontiers in Chemistry, Journal Name: Frontiers in Chemistry Vol. 4; ISSN 2296-2646

Publisher:: Frontiers Research FoundationCopyright Statement

Country of Publication:: United States

Language:: English

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Altered lignocellulose chemical structure and molecular assembly in CINNAMYL ALCOHOL DEHYDROGENASE-deficient rice Martin, Andri Fadillah; Tobimatsu, Yuki; Kusumi, Ryosuke Scientific Reports, Vol. 9, Issue 1 https://doi.org/10.1038/s41598-019-53156-8	journal	November 2019
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Progress in understanding and overcoming biomass recalcitrance: a BioEnergy Science Center (BESC) perspective Gilna, Paul; Lynd, Lee R.; Mohnen, Debra Biotechnology for Biofuels, Vol. 10, Issue 1 https://doi.org/10.1186/s13068-017-0971-1	journal	November 2017
The impact of silicon on cell wall composition and enzymatic saccharification of Brachypodium distachyon Głazowska, Sylwia; Baldwin, Laetitia; Mravec, Jozef Biotechnology for Biofuels, Vol. 11, Issue 1 https://doi.org/10.1186/s13068-018-1166-0	journal	June 2018
Tracking of enzymatic biomass deconstruction by fungal secretomes highlights markers of lignocellulose recalcitrance Paës, Gabriel; Navarro, David; Benoit, Yves Biotechnology for Biofuels, Vol. 12, Issue 1 https://doi.org/10.1186/s13068-019-1417-8	journal	April 2019
Aqueous Ammonia Pre-treatment of Wheat Straw: Process Optimization and Broad Spectrum Dye Adsorption on Nitrogen-Containing Lignin Sipponen, Mika Henrikki; Österberg, Monika Frontiers in Chemistry, Vol. 7 https://doi.org/10.3389/fchem.2019.00545	journal	August 2019
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Lignin Engineering in Forest Trees Chanoca, Alexandra; de Vries, Lisanne; Boerjan, Wout Frontiers in Plant Science, Vol. 10 https://doi.org/10.3389/fpls.2019.00912	journal	July 2019
Mechanism and Compatibility of Pretreated Lignocellulosic Biomass and Polymeric Mixed Matrix Membranes: A Review Amusa, Abiodun; Ahmad, Abdul; Adewole, Jimoh Membranes, Vol. 10, Issue 12 https://doi.org/10.3390/membranes10120370	journal	November 2020
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Topochemical Understanding of Lignin Distribution During Hydrothermal Flowthrough Pretreatment Jung, Seokwon; Trajano, Heather L.; Yoo, Chang Geun ChemistrySelect, Vol. 3, Issue 32 https://doi.org/10.1002/slct.201801837	journal	August 2018
Botryosphaeran – A Fungal Exopolysaccharide of the (1→3)(1→6)-β-D-Glucan Kind: Structure and Biological Functions Dekker, Robert F. H.; Queiroz, Eveline A. I. F.; Cunha, Mario A. A. Biologically-Inspired Systems https://doi.org/10.1007/978-3-030-12919-4_11	book	January 2019
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Modification of plant cell wall chemistry impacts metabolome and microbiome composition in Populus PdKOR1 RNAi plants Veach, Allison M.; Yip, Daniel; Engle, Nancy L. Plant and Soil, Vol. 429, Issue 1-2 https://doi.org/10.1007/s11104-018-3692-8	journal	June 2018
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Systematic parameterization of lignin for the CHARMM force field Vermaas, Josh V.; Petridis, Loukas; Ralph, John Green Chemistry, Vol. 21, Issue 1 https://doi.org/10.1039/c8gc03209b	journal	January 2019
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Phenolic cross-links: building and de-constructing the plant cell wall Mnich, Ewelina; Bjarnholt, Nanna; Eudes, Aymerick Natural Product Reports https://doi.org/10.1039/c9np00028c	journal	January 2020
Lignin biosynthesis: old roads revisited and new roads explored Dixon, Richard A.; Barros, Jaime Open Biology, Vol. 9, Issue 12 https://doi.org/10.1098/rsob.190215	journal	December 2019
Decoupling the direct and indirect effects of climate on plant litter decomposition: Accounting for stress-induced modifications in plant chemistry Suseela, Vidya; Tharayil, Nishanth Global Change Biology, Vol. 24, Issue 4 https://doi.org/10.1111/gcb.13923	journal	January 2018
Characterization of Miscanthus cell wall polymers Schäfer, Judith; Sattler, Melinda; Iqbal, Yasir GCB Bioenergy, Vol. 11, Issue 1 https://doi.org/10.1111/gcbb.12538	journal	August 2018
Host lignin composition affects haustorium induction in the parasitic plants Phtheirospermum japonicum and Striga hermonthica Cui, Songkui; Wada, Syogo; Tobimatsu, Yuki New Phytologist, Vol. 218, Issue 2 https://doi.org/10.1111/nph.15033	journal	March 2018
Overexpression of a Prefoldin β subunit gene reduces biomass recalcitrance in the bioenergy crop Populus Zhang, Jin; Xie, Meng; Li, Mi Plant Biotechnology Journal, Vol. 18, Issue 3 https://doi.org/10.1111/pbi.13254	journal	September 2019
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Lignin from hydrothermally pretreated grass biomass retards enzymatic cellulose degradation by acting as a physical barrier rather than by inducing nonproductive adsorption of enzymes Djajadi, Demi T.; Jensen, Mads M.; Oliveira, Marlene Biotechnology for Biofuels, Vol. 11, Issue 1 https://doi.org/10.1186/s13068-018-1085-0	journal	April 2018
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Dynamical assessment of fluorescent probes mobility in poplar cell walls reveals nanopores govern saccharification Herbaut, Mickaël; Zoghlami, Aya; Paës, Gabriel Biotechnology for Biofuels, Vol. 11, Issue 1 https://doi.org/10.1186/s13068-018-1267-9	journal	October 2018
Combining loss of function of FOLYLPOLYGLUTAMATE SYNTHETASE1 and CAFFEOYL-COA 3-O-METHYLTRANSFERASE1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana Xie, Hongli; Engle, Nancy L.; Venketachalam, Sivasankari Biotechnology for Biofuels, Vol. 12, Issue 1 https://doi.org/10.1186/s13068-019-1446-3	journal	May 2019
Genetic variation of biomass recalcitrance in a natural Salix viminalis (L.) population Ohlsson, Jonas A.; Hallingbäck, Henrik R.; Jebrane, Mohamed Biotechnology for Biofuels, Vol. 12, Issue 1 https://doi.org/10.1186/s13068-019-1479-7	journal	June 2019
Relationship between sugarcane culm and leaf biomass composition and saccharification efficiency Hodgson-Kratky, K.; Papa, G.; Rodriguez, A. Biotechnology for Biofuels, Vol. 12, Issue 1 https://doi.org/10.1186/s13068-019-1588-3	journal	October 2019
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Miscanthus x giganteus Stem Versus Leaf-Derived Lignins Differing in Monolignol Ratio and Linkage Bergs, Michel; Völkering, Georg; Kraska, Thorsten International Journal of Molecular Sciences, Vol. 20, Issue 5 https://doi.org/10.3390/ijms20051200	journal	March 2019
Substrate-Related Factors Affecting Cellulosome-Induced Hydrolysis for Lignocellulose Valorization Wang, Ying; Leng, Ling; Islam, Md Khairul International Journal of Molecular Sciences, Vol. 20, Issue 13 https://doi.org/10.3390/ijms20133354	journal	July 2019
Applications of Lignocellulosic Fibers and Lignin in Bioplastics: A Review Yang, Jianlei; Ching, Yern; Chuah, Cheng Polymers, Vol. 11, Issue 5 https://doi.org/10.3390/polym11050751	journal	April 2019
Modular Engineering of Biomass Degradation Pathways Chaves, Julie E.; Presley, Gerald N.; Michener, Joshua K. Processes, Vol. 7, Issue 4 https://doi.org/10.3390/pr7040230	journal	April 2019
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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
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pretreatment

Current understanding of the correlation of lignin structure with biomass recalcitrance

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