Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance
Multimedia
·
OSTI ID:1332726
ORNL leveraged powerful supercomputing to support research led by University of Oklahoma scientists to identify chemicals that seek out and disrupt bacterial proteins called efflux pumps, known to be a major cause of antibiotic resistance. By running simulations on Titan, the team selected molecules most likely to target and potentially disable the assembly of efflux pumps found in E. coli bacteria cells.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 1332726
- Country of Publication:
- United States
- Language:
- English
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