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Hybrid promoter engineering towards the construction of self-inducible systems for microbial lignin valorization

Journal Article ·
 [1];  [1];  [1];  [1];  [2];  [1]
  1. Sandia National Lab. (SNL-CA), Livermore, CA (United States)
  2. Sandia National Lab. (SNL-CA), Livermore, CA (United States); Joint BioEnergy Institute, Emeryville, CA (United States); Univ. of Minnesota, St. Paul, MN (United States)
Lignin valorization is viewed as a key for the development of a cost effective lignocellulosic biorefinery, and synthetic biology tools would play an important role in the construction of an efficient chassis towards this goal. In this study, we have employed a hybrid promoter engineering approach for the construction of higher strength phenolics inducible promoters.
Research Organization:
Sandia National Laboratories (SNL-CA), Livermore, CA (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA)
DOE Contract Number:
AC04-94AL85000
OSTI ID:
1332660
Report Number(s):
SAND--2016-7801J; 646547
Country of Publication:
United States
Language:
English

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Recent advances in lignin valorization with bacterial cultures: microorganisms, metabolic pathways, and bio-products journal February 2019
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Biotransformation of lignin: Mechanisms, applications and future work journal October 2019
Directed evolution of the PcaV allosteric transcription factor to generate a biosensor for aromatic aldehydes journal November 2019